Ch. 2 - Cells Flashcards

1
Q

The cellular basis of muscular dystrophy is that some of a child’s muscle cells _____.

A

Lack a protein that enables them to withstand the force of contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Select the true statement regarding types of cells.

A

Somatic cells are diploid, meaning that they have two copies of the human genome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Egg cells are _____.

A

Haploid germ cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

A type of vesicle that ferries molecules, such as cholesterol, to lysosomes is an _____.

A

Endosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ribosomes are in the cells of _____.

A

All organisms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The internal architecture of a cell consists of _____.

A

Microtubules, intermediate filaments, and microfilaments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which of the following acts as a quality control center for cells?

A

Endoplasmic reticulum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

In mitochondria, _____.

A

Energy from nutrients is converted into a form that a cell can use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

People with giant axons lose the ability to move and see because _____.

A

They lack a protein, called gigaxonin, which normally breaks down intermediate filaments and recycles their components

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The organelle that is the equivalent of a cellular garbage disposal system is the _____.

A

Lysosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The cell type with the most mitochondria is _____.

A

Muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

During apoptosis, caspases _____.

A

Activate enzymes that cut DNA into same-sized pieces

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

The part of a chromosome that shortens with each cell division, functioning as a “clock,” is the _____.

A

Telomere

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

A cell lacking which type of proteins would be most likely to activate the spindle assembly checkpoint in mitosis?

A

Tubulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Factors that control how often a cell divides include _____.

A

Telomere lengths, hormonal signals, crowding, and growth factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

At the point in the cell cycle when mitosis begins _____.

A

Each chromosome consists of two identical chromatids joined at the centromere

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

An experimental treatment for amyotrophic lateral sclerosis (Lou Gehrig’s disease), which causes gradual loss of the ability to move, sends four genes into cells sampled from a patient’s skin. This procedure reprograms the cells, which are then exposed to molecules and genes that stimulate them to develop as healthy versions of the cells affected in the disease. These cells are implanted into the patient. They are _____.

A

Induced pluripotent stem cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Human embryonic stem cells that are used in research are _____.

A

Cultured in laboratory dishes from inner cell mass cells taken from a very early embryo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

A cell that can divide to give rise to any cell type, including those of membranes that support the developing embryo, is _____.

A

Totipotent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Which of the following bacteria benefits humans?

A

Lactobacillus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Somatic cells that are reprogrammed to into any of several cell types
_____.

A

Induced pluripotent stem cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Stem cells that can self-renew and are found in embryos, fetuses, children, and adults _____.

A

Adult stem cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Stem cells taken from the inner cell mass _____.

A

Embryonic stem cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

You are studying the cytoskeleton in budding yeast, a model organism used in science laboratories. You isolate a mutant that seems to be unable to segregate its chromosomes in mitosis. You know the mutation is in a cytoskeletal component. Which component do you suspect that the mutation is in?

A

Microtubules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Phenylketonuria is a disease in which toxic levels of phenylalanine can accumulate due to low levels of the enzyme phenylalanine hydroxylase. A person with phenylketonuria has a low level of a member of which category of major chemicals in the cell?
Proteins
26
If a species has a haploid number of 16 chromosomes, how many chromosomes would be in a diploid cell from this organism?
32
27
A somatic cell in an organism has 22 chromosomes. How many chromosomes will a germ cell from the same organism have?
11
28
Cells contract, providing movement
Muscle tissues
29
Neurons transmit information
Nervous tissues
30
Tight cell layers form linings
Epithelium
31
Protect, support, bind to cells, and fill spaces throughout the body
Connective tissues
32
It is important to know the cellular basis of a disease because _____.
Knowing what is wrong at the cellular level can suggest possible treatments
33
When a baby with lactase deficiency is given lactose-free infant formula, this is an example of _____.
How knowing the cellular basis of a disease can suggest a treatment for the disease
34
If survivin accumulates, mitosis will occur _____.
Apoptosis checkpoint
35
Inhibits cell cycle until DNA can be repaired _____.
DNA damage checkpoint
36
Checks if the spindle is built and chromosomes are attached to the spindle _____.
Spindle assembly checkpoint
37
After DNA replication copies of the genome are joined at _____.
Centromeres
38
Long strands of chromosomal material in replicated chromosomes are called _____.
Chromatids
39
Centriole microtubules join with other proteins to organize the spindle in structures called _____.
Centrosomes
40
Chromosome tips are called _____.
Telomeres
41
Centromeres part and one chromatid from each pair moves to opposite ends of the cell _____.
Anaphase
42
The membranes around nuclei reform _____.
Telophase
43
DNA coils tightly, shortening and thickening chromosomes _____.
Prophase
44
Chromosomes align along the center of the cell _____.
Metaphase
45
You are studying the cell division in budding yeast, a model organism used in science laboratories. You isolate a mutant that has an uneven number of chromosomes in each cell after mitosis. You know the mutation is in a checkpoint protein. Which checkpoint is most likely affected?
Spindle assembly checkpoint
46
During apoptosis, what organelle releases molecules to increase caspase activity?
Mitochondria
47
A cell that can give rise to every cell type _____.
Totipotent
48
A cell that cannot give rise to every cell type but still has a large number of possible fates _____.
Pluripotent
49
A cell that has only a few developmental choices _____.
Multipotent
50
The Human Microbiome Project studied what type of organisms on and in the human body?
Bacteria
51
What practice introduced bacteria that cause dental caries (cavities) to the human mouth?
Agriculture
52
MNGIE is a rare autosomal recessive human disease characterized by intestinal and ophthalmologic abnormalities. It occurs due to a mutation that leads to inadequate energy production in affected cells. Which organelle's function do you predict is affected in MNGIE?
Mitochondria
53
A diploid cell in G1 contains 5 pairs of chromosomes. During mitosis, how many chromosomes will be lined up on the metaphase plate in this cell?
10
54
Cutis laxa is a connective tissue disorder. One of the causes is abnormal glycosylation of serum proteins. Glycosylation is the addition of a carbohydrate such as a sugar to another molecule. Which organelle do you predict is affected in cutis laxa?
Golgi apparatus
55
_____ provide energy for cells and also contribute to cellular structure.
Carbohydrates
56
_____ form biological membranes, provide insulation, store energy, and form the basis of several types of hormones.
Lipids
57
_____ have many functions in the human body, including blood clotting, muscle contraction, and catalyzing chemical reactions.
Proteins
58
_____ store genetic information that is used to produce proteins and that is passed from generation to generation to give a cell its characteristics.
Nucleic acids
59
Porous sac containing DNA
Nucleus
60
Detoxifies various molecules
Peroxisome
61
Catalyst for protein synthesis Globular subunits of RNA and protein
Ribosome
62
Membrane network; may be associated with ribosomes Site of lipid synthesis and protein folding
Endoplasmic reticulum
63
Stacks of membrane-enclosed sacs Site where sugars are joined to lipids or proteins Site where secretions are stored
Golgi apparatus
64
Two membranes; inner membrane enzyme-studded Releases energy from nutrients
Mitochondrion
65
Information within the _____ is transcribed into mRNA and transported outside the nuclear envelope.
Nucleus
66
Proteins are synthesized on _____ and then enter the _____ where they are further folded and modified.
Ribosomes; rough endoplasmic reticulum
67
The _____ helps produce lipids.
Smooth endoplasmic reticulum
68
Once these molecules are folded and modified, transport vehicles called _____ pinch off and surround them with membranes to be transported elsewhere.
Vesicles
69
The vesicles are moved to the _____ where they are sorted and packaged.
Golgi apparatus
70
Transport vehicles carry the macromolecules to the _____ where they fuse and release their contents to the outside environment.
Plasma membrane