CH 19 Antineoplastic Drugs Flashcards
- Which of the following is NOT a function of a cell?
Regulate temperature
Absorb food
Excrete waste products
Reproduce
Regulate temperature
The functions of the cell include absorbing foods, excreting waste products, and reproducing.
- Which of the following is NOT a specialization performed by cells?
Forming protective coatings and linings for body parts Producing chemicals that control body processes Connecting body parts or creating body movement
Synthesizing minerals and electrolytes
Synthesizing minerals and electrolytes
Specialized functions of the cells are forming protective coatings and linings for body parts, producing chemicals that control body processes, and connecting body parts or creating body movement.
- Which of the following is NOT a type of cell in the human body?
Muscle
Epithelial
Chlorophyll
Connective
Chlorophyll
The four types of cells in the human body are muscle, epithelial, connective, and nerve cells.
- Which of the following terms describes a cell’s ability to divide into two?
Replication
Meiosis
Reproduction
Duplication
Reproduction
Cells have the ability to divide into two when they reach a certain size, called reproduction.
- During disease and trauma, many cells may be damaged, but damaged cells can be replaced through reproduction. This process is called:
replacement.
renewal.
healing.
diffusion.
healing
During disease and trauma, many cells may be damaged, but damaged cells can be reproduced through a process called healing.
- Which of the following statements explains why older adults have special medical needs that include the necessity of adjusting drug dosages for age?
Cells are not easily able to replace themselves.
The process of cell division slows.
Healing takes longer after an accident or illness.
Digestion, energy production, and excretion all slow down.
Digestion, energy production, and excretion all slow down.
Digestion, energy production, and excretion all slow down as the body ages explaining why older adults have special medical needs and why drug doses must be adjusted for age.
- Which of the following terms is used to describe a group of cells working together?
Organs
Systems
Tissues
Groups
Tissues
Tissues are a group of cells of the same type, working together to perform some function.
- Which of the following terms describes two or more tissue types that perform a specific function?
Organs
Systems
Tissues
Groups
Organs
Organs are made up of two or more tissue types that perform a specific function.
- Which of the following terms describes well-organized groups of organs and tissues that perform functions to include breathing, eating, thinking, and regulating body processes?
Organs
Systems
Tissues
Groups
Systems
The important functions that keep the body living—breathing, eating and digesting, thinking, and regulating body processes—are performed by well-organized groups of organs and tissues called body systems.
- The body is built of living cells, and it can manufacture many substances that it needs. Which of the following is the most important substance that the body must take in?
Fiber
Water
Minerals
Vitamins
Water
The most important substance that the body must take in is water.
- Water is the largest component of the fluid inside cells and is called:
Cell wall
Cytoplasm
Nucleus
Mitochondria
Cytoplasm
Cytoplasm is the fluid inside the cell.
- Which of the following chemical activities does NOT involve water?
Gases, liquids, and solids are dissolved in water before traveling through the body.
Absorption involves water.
Heat conservation involves water.
Distribution involves water.
Heat conservation involves water.
Gases, liquids, and solids are dissolved in water before traveling through the body. The processes of absorption, distribution, biotransformation, and excretion all involve water.
- Which of the following terms describes fluid found in spaces between cells; it is also called intercellular fluid?
Lymph
Tissue fluid
Cytoplasm
Plasma
Tissue fluid
Fluid found in spaces between cells is called tissue fluid or intercellular fluid.
- Which of the following is NOT a substance that the body depends on for life processes?
Minerals
Vitamins
Fibers
Proteins
Fibers
Substances the body depends on for its life processes are minerals such as salt and calcium, vitamins, fats, carbohydrates, and proteins.
- Which of the following is the most important defense mechanism of the external immune system?
Mucous membranes
Cilia
Tears
Skin
Skin
The most important defense mechanism of the external immune system is the skin.
- Which of the following terms describes harmful microorganisms?
Pathogens
Antibodies
Invaders
Malignant
Pathogens
The medical term for harmful microorganisms is pathogens.
- Which of the following types of cells produce antibodies, which are proteins that help destroy pathogens as they enter the body?
Erythrocytes
Thrombocytes
Leukocytes
Osteocytes
Leukocytes
Leukocytes are cells that produce antibodies that destroy pathogens as they enter the body.
- Which of the following terms describes proteins that help destroy pathogens as they enter the body?
Antigens
Antibodies
T-cells
Hemoglobin
Antibodies
Proteins that help destroy pathogens as they enter the body are called antibodies.
- Which of the following is NOT a feature of cancer?
Rapid cell growth and reproduction
Invasion of nearby tissue causing destruction
Seeding
Encapsulation and localization
Encapsulation and localization
Rapid cell growth and reproduction, invasion of nearby tissue causing destruction, and seeding are all features of cancer.
- Which of the following terms describes a spreading of malignant cells from one site to other parts of the body?
Diffusion
Infiltrating
Metastasis
Osmosis
Metastasis
The medical term for the spreading of malignant cells from one site to other parts of the body is metastasis.
- Which of the following terms describes an abnormal lump or mass of tissue?
Hematoma
Tumor
Atrophy
Hyperplasia
Tumor
A tumor is an abnormal lump or mass of tissue.
- Which of the following terms is used to describe a well-defined tumor that is contained and will not spread to other parts of the body?
Malignant
Stage III
Benign
Cytostatic
Benign
A well-defined tumor that is contained and will not spread to other parts of the body is called benign.
- Which of the following terms means cancerous, or able to spread to other parts of the body or to invade locally?
Malignant
Diffusion
Osmosis
Benign
Malignant
A cancerous tumor that spreads to other parts of the body or invades locally is called malignant.
- Which of the following gives the best chance of curing cancer?
Radiation
Chemotherapy
Early detection
Surgery
Early detection
Early detection of cancer gives the best chance of curing the disease.
- Which of the following terms describes drug treatment of cancer?
Nuclear medicine
Chemotherapy
Pharmacotherapy
Cytotherapy
Chemotherapy
Chemotherapy is drug therapy for cancer.
- Drugs that are used for chemotherapy are attracted to cells that are rapidly:
absorbing.
multiplying.
metabolizing.
mutating.
multiplying.
Some drugs used for chemotherapy are specifically attracted to cells that are multiplying rapidly.
- Which of the following is NOT an area of the body that has rapidly multiplying cells?
Blood-forming centers
Skin
Linings of the mouth, throat, stomach, and intestines
Genitalia
Genitalia
Areas of the body that have rapidly multiplying cells are the blood-forming centers; the skin; and the linings of the mouth, throat, stomach, and intestines.
- Which of the following is NOT a result of chemotherapeutic drugs killing blood cells?
Patients bruise easily.
Patients are more prone to infection.
Bones break more easily.
The temperature regulatory system breaks down.
The temperature regulatory system breaks down.
Patients receiving chemotherapy often bruise easily because of the destruction of platelets, and they may be prone to infection because white blood cells have been destroyed. In addition, their bones may break easily and heal slowly because cancer drugs weaken the bone tissue.
- Which of the following side effects occur as a result of chemotherapy affecting the skin and the linings of the mouth, throat, stomach, and intestines?
Nausea, vomiting, diarrhea
Anorexia, nausea, diarrhea
Hair loss, nausea, vomiting
Anorexia, diarrhea, hair loss
Hair loss, nausea, vomiting
Hair loss, nausea, and vomiting are side effects of chemotherapy.
- Which of the following describes how chemotherapeutic agents are administered?
Low doses are given continuously over a long period. Cycles of intensive treatment followed by a recovery period are used.
High doses are given continuously over a long period. A high initial dose is given, followed by a lower maintenance dose.
Cycles of intensive treatment followed by a recovery period are used.
Cancer drugs are given in cycles of intensive treatment followed by a recovery period, followed by another intensive treatment.
- Without chemotherapy, after six generations a cancer cell would have produced ______ cancer cells.
128
64
12
6
64
Without chemotherapy, after six generations a cancerous cell would have produced 64 cancer cells. If 1 cell mutates and becomes cancerous the progression would be as follows: 1 cell reproduces to make 2 cells × 2 = 4 cells × 2 = 8 cells × 2 = 16 cells × 2 = 32 cells × 2 = 64 cells.
- Which of the following terms is used to describe the period during which disease symptoms disappear?
Curative
Palliative
Remission
Expected
Remission
The term for when the disease symptoms disappear is remission.
- Which of the following is NOT a term used to describe drugs used against cancer?
Antineoplastics
Cytostatic
Cytotoxic
Cytocidal
Cytocidal
Antineoplastics slow down or kill growing cells. Other terms for anticancer drugs are cytostatic, which means stopping all growth, and cytotoxic, which means poisonous to cells.
- Which of the following terms means able to suppress cell growth and replication?
Cytostatic
Cytocidal
Cytotoxic
Cytopenia
Cytostatic
Suppression of cell growth and replication is called cytostatic.
- Which of the following terms means poisonous to cells?
Cytostatic
Cytocidal
Cytotoxic
Cytopenia
Cytotoxic
Cytotoxic means poisonous to cells.
- Which of the following types of drugs cross-link strands of cellular DNA and interfere with RNA, causing an imbalance of growth that results in cell destruction?
Antimetabolites
Alkylating agents
Antibiotic antitumor drugs
Miotic inhibitors
Alkylating agents
Alkylating agents are drugs that cross-link strands of cellular DNA and interfere with RNA, causing an imbalance of growth that results in cell destruction.
- Which of the following drugs acts as an imposter of a building block necessary in the formation of DNA, thereby interfering with the normal production of DNA and resulting in cell death?
Antimetabolites
Alkylating agents
Antibiotic antitumor drugs
Miotic inhibitors
Antimetabolites
Antimetabolites are structurally similar to a building block necessary in the formation of DNA. The cell accepts this substance; however, since it is an imposter, it interferes with the normal production of DNA, resulting in cell death.
- Which of the following drugs are plant alkaloids that block cell division in the metaphase?
Antimetabolites
Alkylating agents
Antibiotic antitumor drugs
Miotic inhibitors
Miotic inhibitors
Miotic inhibitors are plant alkaloids that block cell divisions in the metaphase.
- Estrogen used to treat postmenopausal cancer, progestin used with cancer of the kidney, androgens used to treat breast cancer, and tamoxifen used in metastatic breast cancer in women are all examples of the use of ______________ to treat cancer.
Antimetabolites
Hormones
Lymphokines
Antibiotic antitumor drugs
Hormones
Estrogen used to treat postmenopausal cancer, progestin used with cancer of the kidney, androgens used to treat breast cancer, and tamoxifen used in metastatic breast cancer in women are all examples of the use of hormones to treat cancer.
- Which of the following drugs should be administered prophylactically before administering a chemotherapy drug?
Antiemetics
Rogaine
Antidiarrheals
Histamine
Antiemetics
Antiemetic drugs should be administered prophylactically before administering a chemotherapy drug for the possibility of vomiting.
- Which of the following is NOT a guideline followed when preparing chemotherapy agents?
Work in a specially ventilated room.
Use strict aseptic technique.
Follow standard precautions when handling chemotherapy drugs.
Use PPE when handling the patient’s vomit, urine, or feces.
Follow standard precautions when handling chemotherapy drugs.
When preparing chemotherapy agents, you must work in a specially ventilated room, use strict aseptic technique, and use PPE when handling the patient’s vomit, urine, or feces.
- Which of the following terms describes irritation of the mucous membranes of the mouth?
Esophagitis
Gingivitis
Periodontal disease
Stomatitis
Stomatitis
Irritation of the mucous membrane of the mouth is called stomatitis.
- Which of the following terms describes a reduction in the number of leukocytes in the blood?
Leukocytosis
Esophagitis
Anemia
Leukopenia
Leukopenia
Leukopenia is the reduction in the number of leukocytes in the blood.