Ch 15

Question 1

Endogenous antigen

Answer 1

Class I MHC, a peptide that shows what’s going on inside the cell

Question 2

Exogenous antigen

Answer 2

Class II MHC, display fragments that also include what has been ingested by phagocytosis

Question 3

B cells mature in

Answer 3

Bone marrow

Question 4

Naïve B cells are found in the

Answer 4

Lymph nodes and are mature. They contain receptors similar to antibodies (with unique binding region)

Question 5

B-cell progression

Answer 5

B-cell -> naïve B cell -> ingest antigen -> B cell activated after confirmation from T cell -> turns into plasma or (some) memory B cells

Question 6

IgM

Answer 6

First antibodies on site, 5 Y linked together (penta), too large to cross placenta, can activate complement

Question 7

IgG

Answer 7

Greatest immune response! Longest half-life, second ones to be made when IgM code changes, monomers - can cross the placenta, can activate complement, Opsonins

Question 8

IgA

Answer 8

Dimers

Question 9

IgE

Answer 9

Opsonins

Question 10

IgE