Ch. 14 Gene Expression: From Gene To Protein Flashcards

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1
Q

What type of cells undergo transcription and translation?

A

Bacterial, archaeal, eukaryotic cells

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2
Q

DNA directs the synthesis of proteins

A

Gene expression

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3
Q

The synthesis of RNA complementary to template strand of DNA

A

Transcription

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4
Q

Provides a nucleotide to nucleotide transfer of information

A

Template strand

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5
Q

The synthesis of a polypeptide whose amino acid sequence is specified by the nucleotide sequence in mRNA

A

Translation

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6
Q

Encode as a sequence of nonoverlaping nucleotide triplets

A

Codons

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7
Q

Codons must be read in the correct….

A

Reading frame

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8
Q

Links RNA nucleotide complementary to a DNA template strand

A

RNA polymerase

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9
Q

Intiates where RNA synthesis starts

A

Promoter

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10
Q

Help eukaryotic RNA polymerase recognize promoter sequences

A

Transcription factors

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11
Q

RNA splicing, 5’ cap and poly-a- tail all are included in…

A

RNA processing

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12
Q

Removed part of the mRNA

A

Introns

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13
Q

Joined part of mRNA

A

Exons

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14
Q

Introns are removed and exons are joined during what process?

A

RNA splicing

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15
Q

Introns are removed and exons are joined by what mechanism?

A

Spliceosomes

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16
Q

Catalytic ability of some RNA molecules

A

Ribozymes

17
Q

A cell translates mRNA message into a protein using what?

A

tRNA

18
Q

An enzyme that bound a specific amino acid with a tRNA

A

Aminoacyl-tRNA synthetase

19
Q

A ribosome is made up of..,

A

rRNA and proteins

20
Q

The formation of peptide bonds between amino acids is catalyzes by rRNA as tRNA move through…

A

A, P, E site

21
Q

Changes in one DNA nucleotide pair

A

Point mutations

22
Q

The replacement of one nucleotide and it’s partner with another pair of nucleotides

A

Nucleotide-pair substitution

23
Q

A change in a nucleotide pair that translates the codon to the same amino acid

A

Silent mutation

24
Q

Substitutions that change one amino acid to another one

A

Missense mutations

25
Q

Targets the protein to the ER

A

Signal peptide

26
Q

An escort that brings the ribosome to a receptor protein built into the ER membrane

A

Signal- recognition particle

27
Q

A change in a codon for an amino acid into a stop codon

A

Nonsense mutation

28
Q

Additions or losses of nucleotide pairs in a gene

A

Insertions and deletions

29
Q

Altering the reading frame of the genetic message wherever the # of nucleotides inserted or deleted is not multiple of three

A

Frameshift mutation

30
Q

Physical and chemical agents that cause damage to DNA and alters genes

A

Mutagens

31
Q

Definition of a gene

A

A gene is a region of DNA that can be expressed to produce a final functional product that is either a polypeptide or an RNA molecule