Ch 14: Drug Abuse Flashcards
Need for increasing amounts to produce the desired effects
physical dependence
Overwhelming desire to repeat the use of a particular drug to produce pleasure or avoid discomfort
psychological dependence
describe substance abuse disorder
Use of the substance interferes with ability to fulfill role obligations
Attempts to cut down or control use fail
Intense craving for the substance
Excessive amount of time spent trying to procure the substance or recover from its use
Development of a reversible syndrome of symptoms following excessive use of a substance
Direct effect on the central nervous system
Disruption in physical and psychological functioning
Judgment is disturbed and social and occupational functioning is impaired.
substance intoxication
Development of symptoms that occurs upon abrupt reduction or discontinuation of a substance that has been used
Symptoms are specific to the substance that has been used.
Disruption in physical and psychological functioning
substance withdrawal
Classes of Psychoactive Substances
Alcohol, Caffeine, Cannabis, Hallucinogens, Inhalants, Opioids, Sedatives/hypnotics, Stimulants, Tobacco
biochemical factor of alcohol addiction
Alcohol may produce morphine-like substances in the brain that are responsible for alcohol addiction.
is alcoholism genetic
yes
psychological factors for addiction/alcoholism
Punitive superego
Fixation in the oral stage of psychosexual development
sociocultural factors of addiction
social learning, conditioning, cultural influences
phase one of alcohol use disorder
Prealcoholic phase: Characterized by use of alcohol to relieve everyday stress and tensions of life
phase two of alcohol use disorder
Early alcoholic phase: Begins with blackouts—brief periods of amnesia that occur during or immediately following a period of drinking; alcohol is now required by the person.
phase three of alcohol use disorder
The crucial phase: Person has lost control; physiological dependence is clearly evident.
phase four of alcohol use disorder
The chronic phase: Characterized by emotional and physical disintegration. The person is usually intoxicated more often than sober
Peripheral neuropathy, characterized by
Peripheral nerve damage Pain Burning Tingling Prickly sensations of the extremities
Thought to result from same B vitamin deficiency that contributes to peripheral neuropathy
alcoholic myopathy
Sudden onset of muscle pain, swelling, and weakness; reddish tinge to the urine; rapid rise in muscle enzymes in the blood
acute myopathy
Gradual wasting and weakness in skeletal muscles
chronic myopathy
Most serious form of thiamine deficiency in alcoholic patients
Wernicke’s encephalopathy
Syndrome of confusion, loss of recent memory, and confabulation in alcoholic patients
Korsakoff’s psychosis
Effect of alcohol on the heart is an accumulation of lipids in the myocardial cells, resulting in enlargement and a weakened condition.
alcoholic cardiomyopathy
Inflammation and pain in the esophagus
esophagitis
Effects of alcohol on the stomach include inflammation of the stomach lining characterized by epigastric distress, nausea, vomiting, and distention
gastritis
Usually occurs 1 or 2 days after a binge of excessive alcohol consumption. Symptoms include constant, severe epigastric pain; nausea and vomiting; and abdominal distention.
acute pancreatitis
Leads to pancreatic insufficiency resulting in steatorrhea, malnutrition, weight loss, and diabetes mellitus
chronic pancreatitis
Caused by long-term heavy alcohol use
Symptoms: Enlarged, tender liver; nausea and vomiting; lethargy; anorexia; elevated white blood cell count; fever; and jaundice. Also ascites and weight loss in severe cases
alcoholic hepatitis
end-stage of alcoholic liver disease and is believed to be caused by chronic heavy alcohol use. There is widespread destruction of liver cells, which are replaced by fibrous (scar) tissue
Cirrhosis of the liver
Complications of cirrhosis of the liver can include
Portal hypertension
Ascites
Esophageal varices
Hepatic encephalopathy
Impaired production, function, and movement of white blood cells
leukopenia
Platelet production and survival are impaired as a result of the toxic effects of alcohol
thrombocytopenia