Ch 14: Blood Flashcards
What type of tissue is blood?
Connective tissue
Whats the roles of blood?
Transport + protection.
What are percentages of blood content, what percent plasma vs blood cells?
Plasma: 55%
Blood cells (rbcs, wbcs platelets: 45%
What amount of total weight does blood represent in adult?
8% of total weight.
What is blood ph?
7.35 - 7.45.
What are the percent contents in the plasma?
92% water, 7% proteins (albumins, globulins, fibrogens), 1% ions (na calcium etc) and a bit degraded products from cell metabolism
Does plasma have coagulation proteins, what about ser?
Plasma does ser doesn’t.
Can plasma proteins pass through blood stream?
No, too big.
How much do fibrogens globulins and albumins each make up in plasma?
Albumins = 53%, globulins = 40%, fibrogens = 7%
How many rbcs are there in adult male vs female?
Male: 5,4 milion per micro meters/mm3
Fem: 4,8 million per micro meters/mm3
Whats the diameter of a hematie?
Diameter 7.8 micro meters, thickness 2.6 micro meters.
Where are rbcs produced and by what process.
Red bone marrow (măduva roșie osoasa) and through erythropoiesis.
Explain the process of erithropoiesis.
- We start with the initial cells, the hemocitoblasts aka stem cells.
- We go through various stages to reach maturity.
- A hormone called erithropoietin regulates partially the production of rbcs.
How long can rbcs survive before being killed by macrophages in liver etc?
About 120 days.
What happens after undoing the rbcs/ destroying them?
1, there now free aa for protein synthesis synthesis.
2, Fe goes to bone marrow to make new Hb, excess Fe stored in liver.
3, hem transformed to biliverdin (green) then to bilirubin (Yellow/orange), then transported from spleen to liver excreted in bile, part is converted to urobilinogen (color of feces), other back to liver to give urine color.
