Ch 13: Drugs for the Urinary System and Fluid Balance Flashcards
The Urinary System
this includes the two kidneys two ureters, a urinary bladder and the urethra
Urea
a byproduct of the proteins by body cells mineral salts, and water
Homeostasis
by eliminating the excess water, the Urinary system helps maintain a proper balance of fluids in the body the best pH is neutral or slightly basic
Ureter
the urine collects in this tube and leads out of the kidneys
Nephrons
are the functional units of the kidney
Urethra
Urine passes out of the body through the Urethra
The bladder usually voids approximately 250 mL at a time
Ph
4.6-8.0 acid base imbalance
Protein
Negative- Renal disease may occur temporarily after activity
Urine
inspected for color clarity and odor
Abnormalities include: red urine is indicative of bleeding in the kidneys or bladder. Cloudy or foamy urine may alert the physician to renal disease of infection. sweet smelling urine indicates diabetes Mellitus
hematuria
Blood in the urine
pyuria
pus in urine
Kidney ureter, bladder (KUB)
X-ray used to evaluate the structures of the kidney such as a lacerated kidney or for the presence of sones
Intravenous Pyelogram (IVP)
uses radiopaque dye to visualize the kidneys, renal pelvis, ureters and bladder, a defect may indicate indicates a tumor, or a problem with glomerular filtration
Residual Urine
urine remaining in the bladder
dysuria
painful urination
Oliguria
decreased urine output of 100 to 400 in a 24 hour period
Anuria
less 100 mL in 24 hrs
Kidney Stones
are formed when salts in the urine form and precipitate the formation of a stone
Urinary Tract Infections (UTI)
Infections in the kidneys, ureters or bladder
older adults are more prone to these due to underlying conditions
Pyelonephritis
kidney infection
Nephritis
inflammation of the kidney
Cystitis
inflammation of the bladder
Ureteritis
inflammation of the ureter
Urethritis
inflammation of the urethra
Renal Failure
Total lack of kidney function
chronic renal failure is progressive irreversible damage of both kidneys, Acute has a rapid onset and can possibly be reversed.
Azotemia
the accululation of nitrogenous wastes products
Dialysis
Medical filtering of the blood using a machine
Diuretics
make the kidneys excrete more urine
electrolytes
electrical ions of dissolved salts carry chemicals through the body’s system
Hypercalcemia VS
Hypocalcemia
High blood calcium levels vs low calcium levels in the blood
Hyperlkalemia
Hypokalemia
High blood potassium levels
Low potassium level
Alkalosis
Means too alkaline or over a pH of 7
Hypernatremia VS Hyponatremia
High blood sodium
Low blood sodium
Acidosis
means too acid, or below normal pH of 7
Acidifiers
add more acid (ammonia chloride, sodium bi phosphate)
Alkalizers
make more alkaline (sodium bicarbonate,)
Antobiotics
UTI: cefaclor (ceclor) cefadoxil monohydrate, Cipro, floxin, NegGram
Diuretics
furosemide (lasix), mannitol (Osmitrol), acetazolamide (Diamox)
Side Effects: lower blood pressure, causes light headedness, dizziness, fatigue, and muscle weakness
Replacement of Electrolytes and Fluids
Potassium (Slow-k, K-Lyte, Kaon), CAlcium (calcium gluconate), magnesium, will always be given with loop diuretics
Indwelling Catheter
remains inside the bladder for an extended amount of time
Urinary Antiseptics
Cipro, Bactrim, Septra, nitrofurntoin (Furadantin,macrodantin)
cefadroxil monohydrate (duracef,ultracef) ampicillin (Omnipen, Principen) phenazopyridine
Trimethoprim/sulfamethoxazole (Bactrim, Septra) Oral,IV
Uses: UTI, otitis media,bronchitis, travelers diarrhea
Action:blocks 2 consecutive steps in the biosynthesis of nucleic acids and proteins essential for many bacteria
Dose:1-2 double strength, tablets taken in 1 dose; 2 regular strength tablets, 4 teaspoons of suspension every 12 hours for 10-14 days, do not give if allergic to sulfa
Side Effects:Nausea, vomiting, diarrhea, skin rashes, anorexia, blood disorders, headache
Cipro flaxacin Cipro (oral)
Uses: UTI, respiratory, bone and skin infections
Action: Inhibits DNA gyrase
Dose: 250-500 mg PO every 12hrs; 400 mg IV every 12 hrs
Side Effects: nausea headache, rash
Nitrofuratonin (Furadantin, Macrodantin) Oral
Uses: UTI
Actions: Interferes with Bacterial Enzyme Systems
Dose: 50-100 mg TID or QID; give with food to avoidgastric irritation; rinse mouth to avoid staining police
Side Effects:Anorexia, nausea, diarrhea, may turn urine brown or darker
cefadroxil monohydrate (Dricef, Ultracef) oral
Uses: UTI
Actions:Inhibits cell wall Sythesis
Dose:500 mg daily
Side Effects:nausea, diarrhea , dyspepsia
ampicillin (Omnipen,Principen)
Oral
Uses: UTI
Actions:Is bactericidal; inhibits, cell wall synthesis
Dose: 1-4 PO daily every 4 hrs
Side Effects:rash itching, shortness of breath, diarrhea, nausea, vomitting
Phenazopyradine (Priidium)
Oral
Uses: Pain with urinary tract irritation or infection
Actions: Anesthetizes mucousa membranes of the urinary tract
Dose:100-200 mg rid p.c.
Side Effects: headache vertigo, discoloration of urine
Hydrochlorothiazide (hydrodiuril) Oral
Uses: Edema, hypertention
Actions:increases sodium and water secretions,
Dose: 25-100 mg 1-2 times daily, give early in day because of increased urination;monitor weight and and fluid intake/output
Side Effects:gastric irritation, muscle wekness Hypokalemia, orthostatic hypotension, pancreatitis
Furosemide (Lasix)
Oral, IM, IV
Uses:Edema, hypertension, chronic renal failure
Actions: is a potent loop diuretic; inhibits reabsorption of sodium and chloride
Dose:20-80 mg PO initially then gradually increased to 600 mg a day in patients, with severely edematious states
Side Effects: Dizziness, headache, dehydration, Anemia, leukopenia, rash, orthostatic hypotension, Hypokalemia
Triamterene (dyenium)
Uses: Edema
Actions:Conserves potassium and excretes sodium
Dose: Individualized 100 mg bid after meals, avoid excessive intake of potassium rich foods
Side Effects:nausea vomitting, weakness, rash, dry mouth,hypotension, dizziness
Potassium (Slow-K,K-lyte, Kaon)
Uses:potassium deficiency
Actions:potassium ion replacement
Dose: 20 mEq/day for prevention of hypokelemia; 4-100 mEq/day or more for treatment of potassium depletion
Side Effects:Nausea, vomitting, diarrhea, abdominal distress, hyperkalemia