Ch. 13 and 14 Flashcards
ATS guidelines for COPD is a
preventable and treatable disease, characterized as airflow limitation
COPD is primarily caused by
cigarette smoke
Chronic productive cough for 3 months and 2 successive years
chronic bronchitis
permanent enlargement of the air sacs distal to the terminal bronchioles w. destruction of bronchial walls
emphysema
The conducting airway are the primary structures that under go change in
chronic bronchitis
As a result _________ inflammation, the __________ walls are narrowed by vasodilation, congestion and mucosal edema
chronic; bronchial
Major pathologic associated w/ chronic bronchitis (5)
- thickening of the walls
- excessive mucous production
- partial of total mucous plugging
- smooth muscle constriction
- air trapping hyperinflation
The weakening and permanent enlargement of the air sacs distal to the terminal bronchioles
emphysema
Major pathologic associated w emphysema
- permananet enlargement and destruction of the air spaces
- destruction of AC membrane
- Weakening of the distal, primarily respiratory bronchioles
- air trapping and hyperinflation
2 types of emphysema
- panacinar (panlobular) emphysema
- centriacinar (centrilobular) emphysema
Most common, emphysema chronic bronchitis, cigarette smoke
centrilobular
Less common, more severe, genetic factor Alpha- anti trypsin deficiency
panlobular
Chronic bronchitis, abnormal weakening and enlargement of the Respiratory bronchioles and alveoli in the proximal portion of the acinus
centrilobular emphysema
Abnormal weakening and enlargement of all air spaces distal to the terminal bronchioles
panlobular
How many people in the US have chronic bronchitis, emphysema or both?
10- million
Risk factors include (4)
- genetic factors
- age/ gender
- lung growth/ development
- exposure to particles
Diagnosis should be considered at what age, and with pts who experience these symptoms
40; dyspnea, chronic cough, sputum production, history of exposure risk factors
3 main spirometry test are to measure the severity of airflow limitation w/ suspected COPD
- FVC
- FEV1
- FEV1/FVC ratio
What the primary goals of a COPD assessment (3)
- Establish the degree of airflow limitation
- Determine the effect of COPD on pt’s health
- Ascertain the risk for future events( exacerbation of hospitalizations)
GOLD recommended the assessment of the features independently (4 ASEC)
- Airway limitation
- Symptoms
- Exacerbation risks
- Comorbidities
GOLD 1 = MILD=
FEV1 Greater than or equal to 80% predicated
GOLD 2= MODERATE =
FEV1 50% - 79% predicted
GOLD 3 = SEVERE=
FEV1 30%-49% predicated
GOLD 4 = VERY SEVERE =
FEV1 Less than or equal to 29% or less than predicated