Ch 13-15 Flashcards

1
Q

Why is an understanding of the motor system important for SLPs

A

Communication is a volitional motor act
Need to understand how it functions normally to know what a deficit is and how to treat it

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2
Q

What makes a movement skilled?

A

Speech is a skilled movement
It is accurate, efficient, and consistent
Helps motor patterns become more automatic
Reduces variability in errors
Reduces mental and physical effort to act in environment

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3
Q

3 types of muscles in mammals

A

Striated
Smoooth -in our organs - autonomic system - does not fatigue
Cardiac - consistent, rhythmic function

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4
Q

what type of muscles is used for voluntary movement?

A

Striated

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5
Q

Which type of muscles requires a great deal of metabolic energy and is susceptible to fatigue

A

Striated

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6
Q

Motor movement plan/pathway

A

Brains have intended goal and plan to achieve it
Makes sure action fits the goal so movement is smooth and coordinated (essential for skilled movement)
Send that message from primary motor cortex via UMN which synapse with LMN in brainstem and spinal cord - sends message via LMN to the muscles (CN and spinal nerves) to move them

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7
Q

Where does communication between the LMN and muscles occur?

A

At the neuromuscular junction (NMJ)

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8
Q

What are LMNs and where do they originate?

A

Originate on the brainstem and in the ventral gray area of spinal cord. Get information from UMN

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9
Q

Describe the NMJ

A

It is where the lower motor axon terminal and the muscle fiber meet.
It is a specialized synapse
Synapses with muscle at the motor end plate
Different from other synapses b/c there is a single presynaptic ap to one post-synaptic ap.
It is ONLY excitatory
Neurotransmitter is acetylcholine

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10
Q

What is a motor unit?

A

The smallest functional unit that the CNS can influence and regulate
Consists of a LMN and the muscle fiber that it innervates

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11
Q

What is the difference between the NMJ and motor unit

A

NMJ is where axon terminals are meeting muscle cell
The motor unit is the entire motor neuron and all the cells that innervates it - it is the final common pathway

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12
Q

Muscle fiber Innervation

A

A LMN can innervates multiple muscle fibers, however, a muscle fiber is only innervated by 1 LMN

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13
Q

Why is a muscle fiber innervated by only 1 LMN?

A

Ensures even a simultaneous effort by entire muscle group that is contracting.
No confusion as to which muscle fiber needs to respond. Directly lined up to help our muscles function simultaneously without recruiting other muscles into the movement

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14
Q

List the 4 systems involved in neuromotor control

A

Primary and premotor cortex
Basal ganglia
Cerebellum
LMN from brainstem - cranial nerves and spinal nerves

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15
Q

Define Innervation ratio. What is the relationship between Innervation ratio and skilled movement

A

Small ratio is used for fine motor movement and helps with decreased effort. Key in speech production and communication.
High ratio is less precise motor movement and more force is involved.

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16
Q

Differentiate between direct and indirect systems

A

Direct - message goes directly from the cortex to the muscle. Involves the primary and premotor cortex and LMN
Indirect - messages go to the body - final common pathway. Coordinating movement and the underlying control of what is happening in the direct motor system. Involves the basal ganglia and cerebellum

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17
Q

Where do UMN fit in

A

Pathways from cortex to LMN - taking information from primary and premotor cortex and the brainstem to connect with LMN at cranial and spinal nerves

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18
Q

6 descending UMN pathways where do they originate from?

A

2 from the cortex
4 from the brainstem
Brainstem are less relevant to skilled movements for speech production

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19
Q

Direct pathway from the cerebrum

A

Direct because they provide a direct link between the motor cortices and LMN
Pathways are: corticospinal and corticobulbar

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20
Q

Where are the cell bodies found for the cst and cbt pathways?

A

Found in the cortical layer V from pyramidal cells

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21
Q

Areas of the cortex that the cst and cbt pathways originate from

A

Primary and premotor cortex
Cingulate motor area
Primary sensory area
Posterior parietal cortex
Sensory gives feedback to guide the motor actions

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22
Q

CST course

A

Originate in primary motor cortex on the precentral gyrus of the frontal lobe
Down through the corona radiata and internal capsule to the crus cerebri at the level of the midbrain
Then pons and decussate at the pyramids of the medulla.
Here they become the lateral and anterior corticospinal tracts

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23
Q

What type of nerves are the LMNs from the CST

A

Spinal nerves

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24
Q

What is the difference in the decussation of the lateral CST vs. the anterior CST

A

Proportions are different
Lateral crosses and goes contralateral - 90%
Anterior is Ipsilateral - 10%

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25
What is the difference in function for the lateral and anterior CST
Lateral sends info to the limbs and extremities Anterior sends info to the trunk, neck, and shoulders
26
Course of CBT
Cortical layer V of the pyramidal - precentral gyrus - corona radiata - internal capsule - crus cerebri - CN nuclei
27
Why is the CBT destination the brainstem?
Because they become cranial nerves
28
What is meant by bilateral Innervation
CN nuclei are being innervated by contra- and Ipsilateral Supports simultaneous function of the musculature Innervates laryngeal, oral and pharyngeal cavities
29
Why does bilateral Innervation occur
Helps to make motor patterns efficient Compensatory mechanism - if there is deficit it might not be as severe
30
What are exceptions to bilateral Innervation
CN 7 and 12 12 is only contralateral 7 is lacking bilateral on the lower portion of the face
31
UMN lesion vs. LMN lesion
Normal function both upper and lower portion of face is fine UMN lesion will not have anything from contralateral so will affect lower facial muscles b/c upper face is also innervated from Ipsilateral side. LMN lesion will see droop on upper and lower face b/c connection is cut off at the muscles.
32
UMN from the brainstem
They are indirect Otherwise known as extra pyramidal tracts Associated with unconscious movement associated with posture, balance, gait and visual orientation
33
4 brainstem tracts
Rubrospinal Vestibule spinal Reticule spinal Tectospinal
34
Rubrospinal tract
Helps activate LMN to help maintain tone and support cortical spinal functioning
35
Vestibulospinal tract
Helps with upright posture
36
Reticulospinal tract
Comes from the reticular formation. Works antagonistically to help regulate tone and posture
37
Tectospinal tract
Comes from the superior colliculi Mediates response to if we hear and see something Visual and auditory stimuli and muscle movement to respond to what we hear/see
38
What parts of the body are disproportionately large in primary motor cortex and why
Face and hands b/c they require skilled movement
39
Why is sensory input to the primary motor cortex important
Sensory input is to help with motor learning We adjust actions based on senses Need sensory input to know what we will do next
40
Describe the location of the premotor cortex
Rostral to primary motor cortex Superior, middle, and inferior gyri Goes down to the lateral sulcus
41
What are the two areas of the premotor cortex and where are they located/
Premotor area PMA - lower part of the premotor cortex Supplementary area SMA - upper part of the premotor cortex to longitudinal cerebral fissure
42
What areas of the CNS provide input to the premotor cortex
Basal ganglia Cerebellum Prefrontal cortex
43
What is the basic function of the PMA
Plan, execute, suppress action
44
What is the basic function of the SMA
Contributes to the ability to do timed tasks - respond and understand Sequencing Helps with planning complex actions
45
What is the role of the cingulate gyrus in speech production
Part of the limbic system Helps process emotions and translate to motor commands Tells if action is appropriate or inappropriate Connects emotion with sensory input and our actions Speech - memory, learning, superlinguistics. If inflection changes based on emotion that is from the cingulate gyrus
46
What is meant by neuroplasticity and what is its significance
See handout 3
47
What is the purpose of indirect motor control systems?
Support and influence behavior that is being executed by direct motor pathway
48
What are the two parts of the indirect motor control system?
Basal ganglia Cerebellum
49
Why are indirect pathways called indirect
B/c they don’t directly synapse with LMN. Help modify activity of LMN b/c of their interaction with the direct pathway
50
What is basal ganglia called?
Selectors of movement
51
What is the role of the basal ganglia as selector of movement
Helps regulate duration of action When action should be interrupted by another action When to end an action
52
What are the 5 structures that comprise the basal ganglia
Caudate nucleus Putanem Globulus pallidus Substantia nigra - produces dopamine and glutamate Subthalamic nucleus - produces glutamate
53
What is the striatum
Caudate nucleus + putanem Produces GABA
54
What structures make up the lenticular nuclei
Globulus pallidus + putanem Produces
55
Functions of neurotransmitters GABA, glutamate, dopamine
GABA - inhibits Glutamate - excitatory Dopamine - modulates
56
Input/output loops of BG
Receive input from cerebral cortex (cortical input) and send output back to cerebral cortex Info through striatum and Subthalamic nucleus and out the Globulus and substantia nigra
57
Direct and indirect pathways of the BG
Entry and output sites are connected to each other by either direct or indirect pathways Both begin with excitatory input from cortex to striatum Both terminate to thalamus from GPi and SNrc. Dopamine is helping alter sensitivity of glutamate
58
Direct pathways of BG lead to…..
Expression of a behavior (movement) GABA is helping reduce production of more GABA Thalamus produces glutamate which is where the movement comes from
59
Indirect pathway of BG lead to….
Inhibition of behavior GABA is reducing GABA which then causes ?????? In the Subthalamic nucleus
60
Connectivity of SNpc (substantia nigra in the pars compacta) to striatum
Dopamine is produced in the Susbtantia nigra Alters sensitivity of striatum to the glutamate arriving from the cortex When striatum receives dopamine and glutamate simultaneously one of two outcomes depending on whether direct or indirect
61
62
Hypokinetic dysfunction see pg 554
Overactivity of the indirect pathway Leads to inhibition of behavior and results in rigidity/slowness Not enough dopamine
63
Hyperkinetic dysfunction - see pg 554
Degeneration in the striatum Results in excessive movement
64
Function of cerebellum
Operates to coordinate and refine movement Involved in motor learning and motor coordination
65
Key sources of input to cerebellum
Premotor and primary cortex - intent to act Peripheral sensory systems - give feedback on actions. Helps with motor learning
66
3 distinct regions of the cerebellum and their functions
1. Vestibulocerebellum - on the flocculonodular lobe - helps with posture and balance 2. Spinocerebellum - at the midline - deals with proprioception from the musculoskeletal system and skin 3. Cerebrocerebellum - lateral hemis - planning, timing, and initiation of movement
67
Cerebellar peduncles and input/output of each
Superior - motor/efferent - info to thalamus to primary motor cortex, red nucleus and reticular formation Middle - afferent/sensory - from pontine nuclei to contralateral cerebellum Inferior - mixed - sensory from spinal cord and brainstem and vestibular nuclei. Sends motor info to vestibular nuclei to help with balance and posture
68
Autonomic nervous system
Motor control system for homeostasis Known as the viscera motor system Controls all internal and involuntary motor operations through 2 divisions: Sympathetic: increases readiness for action (fight or flight) Parasympathetic: return to resting Operates through hormonal and chemical activity orchestrated by the hypothalamus
69
What is motor control?
How we activate our muscles, move our joints, and develop coordinated patterns of motion to accomplish behavioral goals
70
What is a motor skill?
Ability to coordinate voluntary movements through the activity of a variety of muscles in a recognizable pattern for accomplishing a movement goal Use motor skills to execute motor control to accomplish our goals and complete tasks
71
Aspects of motor learning
Sensation in our environment is interpreted into perception and then from perception we turn to action. Sensory info drives our actions Typical reflexes will leap drive actions and learn through what we are doing
72
to learn a skill we need to ….
Understand what we are going to do Plan a pattern of movement to execute motor skill To get desired outcome Sensory info tells you if motor movement is relevant or irrelevant, if we need to adjust or continue motor movement Change motor plans to adapt to what makes you most efficient in what you are doing Optimize motor skills to be more efficient