Cerebellum Ojemann Flashcards

1
Q

what does the cerebellum do

A

calibration of reflexes

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2
Q

vestibular occular rflex

A

controls eye movements to coordinate movement of eyes with movement of head. ie, move head eyes stay fixed on same target.

If you loose hair cell in vestibular apparatus, this reflex would become weakened However, the cerebellum makes sure this doesn’t happen. mossy fibers from vestibular aparatus to cerebullum, then fibers from cerebellum to eye muscles

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3
Q

inputs heading to cerbellumn

A

balance/position/etc - mossy fibers

error inputs - climbing fibers from medulla, contralateral inferior olivary nucleus

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4
Q

cerebellar threes

A

3 gross divisions (2 hemispheres, and a vermis)
3 peduncles
3 functional divisions
3architectural features (cortex, white matter, deep nuclei)
3 cortical layers (molecular, purkinje, granule)
3 principle information processing cells (purkinje, granule, DCN)
3 step circuit
3 general effects of cerebellar damage

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5
Q

3 goss divisions

A

two hemispheres and one vermis, the vermis is tots divided into three as well. nodulus is part of foccular nodular lobe

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6
Q

3 peduncles

A

middle CP - all in put structures (mossy fibers)
inferior CP - from medulla (climbing fibers)
superior CP - fibers from midbrain

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7
Q

3 phylogenetic divisions

A

archicerebellum - flocculus
paleoceebellum - spinalcerebellum
neuocerebellum - cerebocerebellum

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8
Q

where do perkinje cells signal to?

A

to the DCN

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9
Q

parallel fibers?

A

from granular cells, make these t shaped axons that signal to perkinje cells

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10
Q

order of signaling in the cerbellum

A

granular cell signal to perkinjes through parallel fibers, perkinjes signal to dcn

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11
Q

climbing fibers

A

from contralateral inferior olivary nucleus, innervate perkinjes cells, innervate microsomes (stripes), tend to innervate the soma multiple times. Make complex spikes.

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12
Q

mossy fibers and granualr cells

A

mossy fibers signal to granular cells, which then contact perkinje cells, makes simple spikes

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13
Q

what happens when both granual and climbing fibers signal on the same perkinje fibers at the same time?

A

long term depression.

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14
Q

midline vermis input and output

A

output - vastigial nucleus

input - pusture stuff

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15
Q

spinal cerebellar inut and output

A

look it up

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16
Q

cerebrocerebullum input and output

A

look it up

17
Q

paravermis input and output

A

look it up, controls limbs

18
Q

vestibulocerebellum inut and output

A

look it up

19
Q

clarkes nucelus/ column

A

look it up, corollary discharge. copy of sensory signal sent through clarkes nucleus to cerebellum

20
Q

media systems do what?

A

look it up

21
Q

lateral systems do what?

A

look it up

22
Q

synergy

A

ataxia, dymetria, decomposition of movement, dysdiadochokinesia

23
Q

equilibrium

A

look it up

24
Q

muscle tone

A

look it up

25
Q

three rules of cerebellum lesions

A

always ipsilateral
little lesions always have small effects or no effect
one more rule… look it up.

26
Q

HANDS tremor

A
hyotonia
ataxia/asynergia
nystagmus
dysarthria
stance/gate
tremor