Cerebellum Flashcards

1
Q

What separates the anterior and posterior lobes of the cerebellum?

A

The primary fissure

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2
Q

Where are the cerebellar tonsils located?

A

Lie next to the lower medulla above the foramen magnum

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3
Q

Describe the histology of the three layers of the cerebellum

A

Outer layer: pale with mostly axons and few cells
Middle layer: single row of Purkinge cells
Inner layer: thick granule layer

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4
Q

What connections are there from the superior cerebellar peduncle?

A

Only outputs from the cerebellum to the brain and rest of the body

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5
Q

What connections are there from the middle cerebellar peduncle?

A

Inputs from the contralateral cortex and cranial nerves via the pons

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6
Q

What connections are there from the inferior cerebellar peduncle?

A

Input from the spinal cord via spinocerebellar tracts

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7
Q

How do the spinocerebellar tracts enter the cerebellum?

A

Via the inferior cerebellar peduncle

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8
Q

Describe the path of the dorsal (posterior) spinocerebellar tract

A

Travels from the ipsilateral side up the brainstem and into the inferior cerebellar peduncle on the same side (entirely IPSILATERAL)

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9
Q

Describe the path of the ventral (anterior) spinocerebellar tract

A

Carries information from the contralateral side of the body

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10
Q

Describe the path of the anterior/ventral spinothalamic tract

A

Decussates at the level of spinal cord entry but then recrosses in the brainstem and therefore enters the brainstem ipsilaterally to origin

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11
Q

What is the purpose of the dorsal spinocerebellar tract?

A

Carries information from proprioceptors (joints, muscle spindles etc)

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12
Q

What is the purpose of the ventral spinocerebellar tract?

A

Carries information about the state of reflexes and neurones in the spinal cord

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13
Q

What are the names of the deep cerebellar nuclei?

A

Fastigial nucleus, globose nucleus, emboli form nucleus and dentate nucleus

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14
Q

What is the general function of the cerebellum?

A

Involved in aiding the motor cortex in producing accurate and smooth movement

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15
Q

What are the consequences of cerebellar damage?

A

Clumsiness, abnormal fatigue and instability of movement; extraocular eye muscles are particularly affected.

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16
Q

What are the three main functional zones of the cerebellum?

A

Vestibulocerebellum, spinocerebellum and cerebrocerebellum

17
Q

What makes up the vestibulocerebellum?

A

The flocculonodular lobe

18
Q

What it is the function of the vestibulocerebellum?

A

To coordinate head and eye movements and control the balance of the head via the vestibulospinal tracts

19
Q

What makes up the spinocerebellum?

A

Anterior lobe and the vermis (with fastigial and interposed deep nuclei)

20
Q

What is the function of the spinocerebellum?

A

Controls locomotion and limb coordination via lateral vertibulospinal and reticulospinal tracts

21
Q

What makes up the cerebrocerebellum?

A

Posterior lobe of cerebellum and dentate nuclei; input from cerebral cortex via middle cerebral peduncle and output to the central thalamus via the superior cerebral peduncle

22
Q

What is the function of the cerebrocerebellum?

A

Involved in coordinating movement e.g.speech, voluntary movement of hands and arms and hand-eye coordination

23
Q

What are three three main cerebellar syndromes?

A

Floculonodular syndrome, anterior lobe syndrome and neocerebellar syndrome

24
Q

What is a common cause of flocculonodular syndrome?

A

Medulloblastoma - usually originating the floor of the 4th ventricle . Most common in young children

25
Where do medulloblastomas usually originate?
In the floor of the 4th ventricle
26
What are the clinical symptoms of flocculonodular syndrome?
Poor balance and disordered eye movements, ataxic gate
27
What are the clinical symptoms of anterior lobe syndrome?
Incoordination of the limbs (dysdiadochokinesia)
28
What is a common cause of anterior lobe syndrome?
Alcoholism due to malnutrition and lack of B vitamins
29
What are the clinical symptoms of neocerebellar syndrome?
Loss of hand-eye coordination, dysmetria (inaccurate reaching), intention tremor, slurred speech
30
What are the common causes of neocrebellar syndrome
Stroke, tumour and degenerative disease
31
What are the symptoms of cerebellar stroke?
Headache, eye changes (nystagmus, constriction or ptosis), dysarthria (weakened muscles of the mouth --> slurred speech), ataxia and arm weakness and incoordination