cerebellum Flashcards

1
Q

cerebellar fun facts

A

little brain latin , more than half neurons here, regular cytoarchitecture throughout/animals, ongoing motion and thoughts

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2
Q

overview of cerebellar circuit

A

upper motor in M1 sends signal to contra cerebellar hemisphere, as well as to lower motor
cerebellar recieves ipsi feedback from proprioception
compares signals, feedback to M1

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3
Q

cerebellar anaotmy

A

arbor vitae white matter
highly folded gray matter

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4
Q

3 subdivisions of cerebellum

A

folcculonodular lobe, anterior lobe, posterior lobe

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5
Q

flocculonodular lobe functons

A

“vestibulocerebellum”
balance/eye movements, input from vestublar nuclei and output to fastigial nucli and vestibular nuceli, then to LMN

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6
Q

anterior lobe

A

spincocerebellum, error and movement coord and motor execution
input from proprioception and output to interposed nuclei and descending motor paths

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7
Q

posterior lobe

A

cerebrocerebellum/neocerebellum
input from cortex (motor plan)
output to dentate nucleus/thalamus/cortex

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8
Q

3 deep nuclei

A

fastigial = output of vestibulo (vermis, most medial), send to motor execution paths (descending/extrapyramidal)
interposed = output of spino, send to motor execution paths (descending/extrapyramidal)
dentate = output of cerebro (most lateral), send to motor cortices for motor planning

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9
Q

3 peduncles

A

superior = efferent to cortex (error feedback)
middle = afferent, input from cortex/pons (copy of command)
inferior = a/efferent about body position, send to floc. lobe (proprioception)

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10
Q

3 layers of cerebellum

A

molecular = axons/inter
purkinje = single cell row
granular = densely packed granule cells and interneurons

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11
Q

3 neuron types

A

granule cells = form parallel fibers
purkinje cells = project to deep nuclei (dentate/inter/fast)
inhibitory neurons = basket/stellate/golgi

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12
Q

2 types of input

A

both are excitatory onto purkinje
climbing fibers from inf. olive
mossy fibers from spinal cord/cortex via pons
mossy input to granule cells about voluntary movements

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13
Q

cerebellar plasticity

A

when a climbing fiber synapses with a parallel fiber, parallel is weakened
parallel synapses onto purkinje
Marr-Albus-Ito motor learning theory = granule cells (parallel) give continuous info about body, when error, climbing fires which turn off parallel (inf. olive does error)

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14
Q

cerebellar damage

A

balance, nystagmus, wide gait, land and mood too

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