central nervous system

Question 1

infections of CNS

Answer 1

• encephalitis
• meningitis
• polio (paralysis)
• post infect encephalomyelitis
• tse

Question 2

most viruses and bacteria invade CNS by

Answer 2

blood stream

Question 3

virus that reaches CNS by neural route

Answer 3

rabies

Question 4

virus ___ symptoms while bacteria ___ symptoms

Answer 4

virus does NOT show symptoms while bacterial ALWAYS shows symptoms

Question 5

location of encephalitis

Answer 5

brain

Question 6

location of paralysis

Answer 6

anterior horn of spinal cord

Question 7

location of meningitis

Answer 7

meninges

Question 8

location of poster infectious encephalomyelitis

Answer 8

brain

Question 9

virus that causes encephalitis

Answer 9

• hsv
• arbo
• rabies

Question 10

virus causes paralysis

Answer 10

-entero (esp polio)

Question 11

virus that causes meningitis

Answer 11

• enteroviruses*
• hsv
• mumps
• hiv
• adeno

Question 12

virus that causes post infectious encephalomyelitis

Answer 12

• measles
• rubella
• vzv

Question 13

specific symptom of encephalitis

Answer 13

FOCAL NEUROLOGICAL SIGNS AND COMA

Question 14

specific symptoms of paralysis

Answer 14

paralysis

Question 15

specific symptoms of meningitis

Answer 15

neck and back stiffness

Question 16

site of latency of herpes simplex virus (HSV) is

Answer 16

sensory nerve ganglia in dorsal root

Question 17

most cases of encephalitis is

Answer 17

HSV-1 reactivation

Question 18

gold standard for diagnosis of hsv encephalitis

Answer 18

pcr

Question 19

treatment for hsv enc

Answer 19

acyclovir

Question 20

most people with hsv enc have

Answer 20

significant neurological sequelae

Question 21

key viruses for arbovirus enc

Answer 21

• 3 alphaviruses (togaviridae) (EEE, VEE, WEE)
• 2 flaviviridae (SLE, WNV)
• 1 bunyaviridae (LAC)

Question 22

arboviruses are transmitted via

Answer 22

mosquitoes **NO HUMAN TO HUMAN TRANSMISSION

Question 23

leading cause of encephalitis worldwide

Answer 23

arboviruses

Question 24

most deadly arbovirus encephalitis

Answer 24

eastern equine encephalitis

Question 25

diagnosis for arbovirus enc

Answer 25

antibody/serology

Question 26

hsv meningitis

Answer 26

• hsv-2 genital infection
• self-limited
• no neurological sequelae

Question 27

furious rabies

Answer 27

• most common

- muscle contractions, hydrophobia

Question 28

dumb or paralytic rabies

Answer 28

-paralysis

Question 29

stages of rabies

Answer 29

1. paraesthesia
2. either furious or dumb/paralytic
3. coma
4. death

Question 30

diagnosis for bacterial meningitis

Answer 30

lumbar puncture (spinal tap)

Question 31

treatment for bacterial meningitis

Answer 31

• antibiotics

- steroids

Question 32

bacteria that spread bacterial meningitis

Answer 32

• Strep pneumonia
• neisseria meningitidis
• h influenza

Question 33

prevention for h influenza and n meningitidis

Answer 33

rifampin or cephalosporin (3rd gen) or vaccine

Question 34

prevention for group b strep

Answer 34

ampicillin during labour