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DDS1-microbio > central nervous system > Flashcards

central nervous system Flashcards

1
Q

infections of CNS

A
  • encephalitis
  • meningitis
  • polio (paralysis)
  • post infect encephalomyelitis
  • tse
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2
Q

most viruses and bacteria invade CNS by

A

blood stream

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3
Q

virus that reaches CNS by neural route

A

rabies

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4
Q

virus ___ symptoms while bacteria ___ symptoms

A

virus does NOT show symptoms while bacterial ALWAYS shows symptoms

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5
Q

location of encephalitis

A

brain

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6
Q

location of paralysis

A

anterior horn of spinal cord

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7
Q

location of meningitis

A

meninges

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8
Q

location of poster infectious encephalomyelitis

A

brain

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9
Q

virus that causes encephalitis

A
  • hsv
  • arbo
  • rabies
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10
Q

virus causes paralysis

A

-entero (esp polio)

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11
Q

virus that causes meningitis

A
  • enteroviruses*
  • hsv
  • mumps
  • hiv
  • adeno
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12
Q

virus that causes post infectious encephalomyelitis

A
  • measles
  • rubella
  • vzv
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13
Q

specific symptom of encephalitis

A

FOCAL NEUROLOGICAL SIGNS AND COMA

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14
Q

specific symptoms of paralysis

A

paralysis

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15
Q

specific symptoms of meningitis

A

neck and back stiffness

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16
Q

site of latency of herpes simplex virus (HSV) is

A

sensory nerve ganglia in dorsal root

17
Q

most cases of encephalitis is

A

HSV-1 reactivation

18
Q

gold standard for diagnosis of hsv encephalitis

19
Q

treatment for hsv enc

20
Q

most people with hsv enc have

A

significant neurological sequelae

21
Q

key viruses for arbovirus enc

A
  • 3 alphaviruses (togaviridae) (EEE, VEE, WEE)
  • 2 flaviviridae (SLE, WNV)
  • 1 bunyaviridae (LAC)
22
Q

arboviruses are transmitted via

A

mosquitoes **NO HUMAN TO HUMAN TRANSMISSION

23
Q

leading cause of encephalitis worldwide

A

arboviruses

24
Q

most deadly arbovirus encephalitis

A

eastern equine encephalitis

25
diagnosis for arbovirus enc
antibody/serology
26
hsv meningitis
- hsv-2 genital infection - self-limited - no neurological sequelae
27
furious rabies
- most common | - muscle contractions, hydrophobia
28
dumb or paralytic rabies
-paralysis
29
stages of rabies
1. paraesthesia 2. either furious or dumb/paralytic 3. coma 4. death
30
diagnosis for bacterial meningitis
lumbar puncture (spinal tap)
31
treatment for bacterial meningitis
- antibiotics | - steroids
32
bacteria that spread bacterial meningitis
- Strep pneumonia - neisseria meningitidis - h influenza
33
prevention for h influenza and n meningitidis
rifampin or cephalosporin (3rd gen) or vaccine
34
prevention for group b strep
ampicillin during labour

DDS1-microbio (10 decks)

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