central nervous system Flashcards by Suraya Dhalla | Brainscape

Q

infections of CNS

A

encephalitis
meningitis
polio (paralysis)
post infect encephalomyelitis
tse

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Q

most viruses and bacteria invade CNS by

A

blood stream

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Q

virus that reaches CNS by neural route

A

rabies

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Q

virus ___ symptoms while bacteria ___ symptoms

A

virus does NOT show symptoms while bacterial ALWAYS shows symptoms

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Q

location of encephalitis

A

brain

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Q

location of paralysis

A

anterior horn of spinal cord

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Q

location of meningitis

A

meninges

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Q

location of poster infectious encephalomyelitis

A

brain

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Q

virus that causes encephalitis

A

hsv
arbo
rabies

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Q

virus causes paralysis

A

-entero (esp polio)

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Q

virus that causes meningitis

A

enteroviruses*
hsv
mumps
hiv
adeno

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Q

virus that causes post infectious encephalomyelitis

A

measles
rubella
vzv

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Q

specific symptom of encephalitis

A

FOCAL NEUROLOGICAL SIGNS AND COMA

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Q

specific symptoms of paralysis

A

paralysis

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Q

specific symptoms of meningitis

A

neck and back stiffness

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Q

site of latency of herpes simplex virus (HSV) is

A

sensory nerve ganglia in dorsal root

Q

most cases of encephalitis is

A

HSV-1 reactivation

Q

gold standard for diagnosis of hsv encephalitis

A

pcr

Q

treatment for hsv enc

A

acyclovir

Q

most people with hsv enc have

A

significant neurological sequelae

Q

key viruses for arbovirus enc

A

3 alphaviruses (togaviridae) (EEE, VEE, WEE)
2 flaviviridae (SLE, WNV)
1 bunyaviridae (LAC)

Q

arboviruses are transmitted via

A

mosquitoes **NO HUMAN TO HUMAN TRANSMISSION

Q

leading cause of encephalitis worldwide

A

arboviruses

Q

most deadly arbovirus encephalitis

A

eastern equine encephalitis

Q

diagnosis for arbovirus enc

A

antibody/serology

Q

hsv meningitis

A

hsv-2 genital infection
self-limited
no neurological sequelae

Q

furious rabies

A

most common

- muscle contractions, hydrophobia

Q

dumb or paralytic rabies

A

-paralysis

Q

stages of rabies

A

paraesthesia
either furious or dumb/paralytic
coma
death

Q

diagnosis for bacterial meningitis

A

lumbar puncture (spinal tap)

Q

treatment for bacterial meningitis

A

antibiotics

- steroids

Q

bacteria that spread bacterial meningitis

A

Strep pneumonia
neisseria meningitidis
h influenza

Q

prevention for h influenza and n meningitidis

A

rifampin or cephalosporin (3rd gen) or vaccine

Q

prevention for group b strep

A

ampicillin during labour