Cellular Respiration Flashcards

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1
Q

Cellular respiration

A

an ATP generating process that occurs within cells. Energy is extracted from energy rich glucose to form ATP from ADP and P. The chemical equation is
C6H12O6 + 6O2 -> 6CO2 + 6H2O + energy

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2
Q

Aerobic respiration

A

cellular respiration in the presence of O2. It is divided into three components: glycolosis, the Krebs cycle and oxidative phosphorylation.

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3
Q

Glycolosis

A

the decomposition of glucose to pyruvate. Nine intermediate products are formed. and each one is catalyzed by an enzyme. Mg2+ are cofactors that promote enzyme activity.

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4
Q

Glycolosis Steps

A

1) 2 ATP are added: First several steps require energy input. This changes glucose in preparation for subsequent steps.
2) 2 NADH are produced. NADH, a coenzyme, forms when NAD+ combines with the two energy rich electrons. and H+ (obtained from an intermediate). As a result NADH is an energy rich molecule.
3) 4 ATP are produced
4) 2 pyruvate are formed
Summary: glycolosis takes 1 glucose and turns it into 2 pyruvate, 2 NADH adn a net of 2 ATP. Occurs in cytosol.

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5
Q

The Krebs Cycle

A

details what happens to pyruvate the end product of glycolosis.
3 NADH, 1 FADH2, 1 ATP AND CO2.
Begins with acetyl CoA combines with OAA to form citrate. There are seven intermediate products along the way. 3 NADH and 1 FADH2 are made and CO2 released.
also known as Citric acid cycle and TCA cycle
occurs in mitochondria

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6
Q

Step leading to Krebs cycle

A

1) Pyruvate to acetyl CoA.: In a step leading up to the actual Krebs cycle, pyruvate combines with coenzyme A (CoA) to produce acytal CoA. In that reaction 1 NADH and 1 CO2 are also produced.

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7
Q

OAA

A

oxaloacetate

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8
Q

FADH2

A

like NADH is a coenzyme, accepting electrons during a reaction

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9
Q

CO2 from Krebs Cycle is

A

the CO2 animals exhale when they breathe.

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10
Q

Oxidative Phosphorylation

A

the process of extracting ATP from NADH and FADH2. Electrons from NADH and FADH2 pass along an electron support chain. The final electron acceptor of the ETC is oxygen. The 1/2 O2 accepts the two electrons and together with 2 H+ forms water.
occurs in mitochondria

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11
Q

Electron transport chain

A

the chain consists of proteins that pass these electrons from one carrier protein to the next. Along each step of the chain the electrons give up energy used to phosphorylate ADP to ATP.

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12
Q

How much ATP can be produced from NADH

A

it produces enough electrons to produce 3 ATP

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13
Q

FADH2 produces enough electrons to produce __ ATP

A

2 ATP

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14
Q

Cytochrome C

A

one of the carrier proteins (includes iron) in the ETC is so ubiquitous among living organisms that approximately 100 amino acid sequence of the protein is often compared among species to access genetic relations

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15
Q

Mitochondria distinct areas

A

Outer membrane, intermembrane space, inner membrane, matrix

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16
Q

Outer membrane of mitochondria

A

this membrane is like the plasma membrane consists of a double layer of phospholipids

17
Q

Intermembrane space of mitochondria

A

this is the narrow area between the inner and outer membranes. H+ ions (protons) accumulate here

18
Q

Inner membrane of mitochondria

A

the second membrane, also a double phospholipid bilayer, has cristae. Oxidative phosphorylation occurs here. Within the membrane and its cristae the electron transport chain removes electrons from NADH and FADh2 and protein complexes transports H+ ions from the matrix to the intermembrane space.

19
Q

Matrix

A

the matrix is the fluid material that fills the area inside the inner membrane. the Krebs Cycle and the conversion of pyruvate to acetyl CoA occur here.
-The Krebs cycle produces NADH and FADH2 in addition CO2 is generated and substrate level phosphorylation occurs to produce ATP.

20
Q

Chemiosmosis

A

the mechanism of ATP generation occurs when energy is stored in the form of a proton concentration gradient across a membrane

21
Q

ATP synthase generates ATP in mitochondria explain

A

ATP synthase a channel protein in the inner membrane, allows the protons in the intermembrane compartment to flow back into the matrix. The protons moving through the channel generate the energy for ATP synthase to produce ATP.

22
Q

how pH is created in mitochondria

A

as H+ are transferred from the matrix to the intermembrane space, the concentration of H+ increase (and pH decreases) in the intermembrane space and decreases in the matrix (pH increases)

23
Q

Two types of phosphorylation

A

substrate level and oxidative, two metabolic processes for generating ATP occur

24
Q

Substrate level phosphorylation

A

occurs when a phosphate group and its associated energy is transferred to ADP to form ATP. the substrate molecule (molecule within the substrate group) donates the high energy phosphate group. Occurs in glycoyisis

25
Q

Oxidative phosphorylation

A

occurs when a phosphate group is added to ADP to form ATP but the energy for the bond does not accompany the phosphare group. Instead the ETC supplies the engery.

26
Q

Anaerobic respiration

A

the method cells use when there is no oxygen present and no electron acceptor exists to accept electrons at the end of ETC ceasing Krebs cycle and glycolosis. Occurs in the cytosol. two metabolic pathways are alcohol and lactic acid fermentation.

27
Q

Alcohol fermentation (fermentation)

A

occurs in plants, fungi (yeasts) and bacteria

1) pyruvate to acetaldehyde. for each pyruvate 1 CO2 and 1 acetalhyde are produced, the CO2 formed is the source of carbonation in fermented drinks like beer and champagne
2) acetaldehyde to ethanol. the important part of this step is the energy in NADH is used to drive this reaction releasing NAD+. For each acetaldehyde, 1 ethanol is made and 1 NAD+ is produced

28
Q

Lactic Acid fermentation

A

A pyruvate is converted to lactate, and in the process, NADH gives up its electrons to form NAD+, as in alchohol fermentaion, the NAD+ can now be used as glycolysis. In animals most lactate is transported to the liver where it is converted back to glucose when surplus ATP is available.