Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Cellular Biology and Biochemistry > Cell movement > Flashcards

Cell movement Flashcards

You may prefer our related Brainscape-certified flashcards:
AP® Biology flashcards Biology 101 flashcards
1
Q

Which filament is involved in cell movement?

A

Actin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What controls actin movement?

A

Actin-binding proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Name the three proteins a bacteria requires to move between cells

A

Nucleation
Recycling
Capping

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe the energetics of nucleation

A

Forming dimers and trimers is energetically unfavourable

Once formed the trimer rapidly elongates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the arp2/3 complex?

A

A 7 protein complex that contains 2 actin-related proteins

Forms a trimer allowing polymerisation of new filaments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Name the three different types of capping protein

A

Gelsolin

gCap39

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is a capping protein?

A

A dimer of a alpha/beta subunits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Describe gelsolin

A

An actin binding protein that severs actin filaments and binds to the plus end

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Describe gCap39

A

Non-muscle capping protein

Does not sever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the role of a capping protein?

A

Switches polymerisation on and off
Restricts polymerisation of new filament
Prevents disassembly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Give an example of a capping protein as an on/off switch

A

Activating platelets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What two proteins recycle monomers?

A

ADF/Cofilin

Profilin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the role of ADF/Cofilin?

A

Binds to actin monomers in the ADP form
Binds to actin filaments and destabilises them
Appears to be required for actin assembly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the role of profilin?

A

Profilin adds monomers to the actin filament

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How does profilin work?

A

Profilin binds to actin monomers
Profilin binding favours ATP-actin
Profilin promotes exchange of ADP to ATP
Profilin-ATP-actin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are lamellipodia?

A

Used in protusion
Actin polymerisation driven
Actin filaments are branched
Formed by nucleation with prevention of capping

17
Q

What are filopodia?

A

Used in sensing the environment e.g neuron pathfinding
Actin polymerisation driven
Long parallel bundles of filaments
Often accompanied by lamellipodia

18
Q

What is the difference in structure of lamellipodia and filopodia?

A

Lamellipodia are unbundled

Filopodia are highly bundled

19
Q

What is a stress fibre?

A

A bundle of actin and myosin

20
Q

What are the three stages to moving a cell?

A

Protrusion
Translocation
Detachment

21
Q

Describe the process of protrusion

A

Actin polymerisation
Organisation of actin
Membrane insertion or protrusion

22
Q

Describe the process of translocation

A

Formation of new adhesions via integrins
Actin-myosin contractility of stress fibres
Traction generated by intergrins

23
Q

Describe the process of detachment

A

Actin-myosin contractility
Traction generated by adhesion
Proteases degrade contacts

24
Q

Where is the Arp2/3 complex found?

A

The leading edge

Cellular Biology and Biochemistry (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions