cell membranes Flashcards
1
Q
what do cell membrane drugs work best against?
A
Gram -
2
Q
what is the butter leaflet of gram- made of?
A
1.lipid A
2.core polysaccharides
3.O-specific polysaccharide
3
Q
what does lipid A do and consist of?
A
functions the same as a phosphate but has multiple branched fatty acids, 2 glucosamine, one phosphate
4
Q
what does the core polysaccharide consist of?
A
sugar KDO(3), binds to glucosamine, the rest of sugars are the same in every gram -
5
Q
what does the O-specific polysaccharide consist of?
A
series of sugars that repeat, each organism can have different series (O-antigen)
6
Q
what to all IV’s and vaccines have to be?
A
pyrogen free- can cause fever and shock