Cell fate and fate mapping

Question 1

What is cell fate?

Answer 1

what cells will normally become / develop into during development.

Question 2

What is an autonomous mechanism in which cells can become different?

Answer 2

Intrinsic factors- e.g. segregration of cytoplasmic components.

Question 3

What is the non-autonomous mechanism that causes cells to become different

Answer 3

Extrinsic factors/ signals - cell-cell signalling

Question 4

what is lineage?

Answer 4

The sequence of cell divisions that give rise to a cell

Question 5

What are the 3 methods of making a fate map

Answer 5

observation, application of a label/marker, natural pigmentation

Question 6

What is the difference between mosaic and regulative development?

Answer 6

In mosaic development cells become determined early in development (autonomous) and in regulative development the cells do not become determined early in development. (non-autonomous)

Question 7

What to vegetal cells usually give rise to?

Answer 7

endoderm

Question 8

What do animal cells give rise to in isolation and in embyro?

Answer 8

In isolation give rise to epidermis but in the embryo they give rise to epidermis and neural cells.

Question 9

Give 2 ways of testing cell commitment

Answer 9

transplantation, or culture in isolation