Cell division Flashcards
Mitosis Stage
“Preparation”. Nucleus breaks down and chromosomes condense.
Spindle apparatus with microtubules forms, attaching to the sister chromatids, which are joined by centromeres.
Prophase
Mitosis Stages
“Middle”.
Chromosomes aligned at center of cell
Metaphase
Mitosis Stages
“Apart”.
Sister chromatids separate, moving to opposite poles.
Failure to separate is called nondisjunction and results in aneuploidy.
Anaphase
Mitosis Stages
Nuclear membrane re-forms. Cytokinesis occurs.
Telophase
Meiosis II Stages
Chromosomes condense again. Centrosomes separate and move to opposite poles.
Prophase II
Meiosis II Stages
Spindle fibers attach at centromeres and line the centrosomes in center of cell (but perpendicular to metaphase I).
Metaphase II
Meiosis II Stages
Sister chromatids are separated and move to opposite poles of cells.
Anaphase II
Meiosis II Stages
Cytokinesis occurs. Four equal haploid daughter cells are formed.
Telophase II
Sequence of the cell cycle
G1 → (S or G0) → G2 → M
Cell cycle
“Cell growth.” Makes cellular components like organelles and proteins.
Decides whether to divide (proceed to S) or not divide (proceed to G0).
G1
Cell cycle
“Synthesis”. DNA replication occurs.
S
Cell cycle
“Cell cycle arrest.” Non-growth phase. Highest protein production.
G0
Cell cycle
“Cell growth”. Makes more proteins and organelles.
G2/M checkpoint checks for chromosomal and DNA replication errors and checks if there is enough mitosis promoting factor to proceed.
G2
Cell cycle
“Mitosis.” Prophase, metaphase, anaphase, and telophase occur. Cytokinesis occurs.
M
Meiosis I vs Meiosis II
Meiosis I: Homologous chromosomes separate.
Meiosis II: Sister chromatids separate.