Cell Cycle Regulation Flashcards
________: a protein that is synthesized and then degraded in concert with events of the cell cycle; binds to a CDK to promote events of the cell cycle
Cyclin
How are cyclin protein levels increased in a cell?
Gene expression (transcription + translation)
How are cyclin protein levels decreased in a cell?
Protein degradation (protein breakdown)
Cyclin | When Protein Levels are High
————–|——————————————–
|
D |
|
G1, S, G2
Cyclin | When Protein Levels are High
————|——————————————
|
E |
|
Late G1, early S
Cyclin | When Protein Levels are High
————–|——————————————–
|
A |
|
S, G2
Cyclin | When Protein Levels are High
————–|——————————————–
|
B |
|
G2, early M
_________: (_________), a kinase protein that becomes active after binding to a cyclin
CDK, cyclin-dependent kinase
The concentration of CDK in the cell is constant / changes over time
Is constant
what three molecules does CDK need to bind to in order to be active and carry out its function?
1.
2.
3.
Cyclin, ATP, Target protein