Cell Cycle, Mitosis, & Meiosis (Biology Summative) Flashcards
What is telomere?
The tip of a chromosome
Oogenesis
Production of female gametes (ova)
Starts during fetal development
Cell Division vs Nuclear Division
What is mitosis?
The division of the nucleus of the cell into two new nuclei
Explain
What happens in Synthesis (S) stage?
Replication of DNA
These are the cell’s control systems.
From these, the cell cycle stops until a go-ahead signal is received.
Checkpoints
* G1 Checkpoint (G1 to S)
* G2 Checkpoint (G2 to M)
* Spindle or M Checkpoint (Meta to Ana)
Explain
What happens in Gap 1 (G1)?
The cell just finished dividing, so in Gap 1, it is recovering from mitosis
Meiosis II
Telophase II and Cytokinesis II
- The cells split in half
- Four non-identical haploid daughter cells are produced from one original diploid cell
Meiosis II
Anaphase
- Centromeres split
- Sister chromatids are pulled to the poles
Meiosis I
Prometaphase
- Spindle fibers starting to attach to the chromosomes through its centromeres
- The chromosomes continue to condense
What are diploids?
- two sets of chromosomes (2n)
- In humans, 23 pairs or 46 chromosomes in total
- In this checkpoint, the DNA is examined for errors
- If errors are detected, the cell attempts to complete replication or repair damaged DNA in this checkpoint
- If the damage is irrepairable, the cell may undergo through apoptosis (cell suicide) to avoid replication of damaged DNA
G2 Checkpoint
What happens in Gap 2 (G2)?
- Preparation for Mitosis
- Organelles are replicated
- More growth occurs
Why does the activity of cyclin-dependent kinases fluctuate during the cell cycle?
Because they are controlled by cyclins, so named because their concentrations vary with the cell cycle.
Difference of Mitosis and Meiosis
- Meiosis produces n while mitosis produces 2n
- Daughter cells produced through mitosis are genetically identical, opposite to meiosis
- In meiosis, division occurs twice but replication only once
Meiosis II
Telophase II and Cytokinesis II
- The cells split in half
- Four non-identical haploid daughter cells are produced from one original diploid cell
What is synapsis?
pairing of homologous chromosomes forming a tetrad (4 homologous chromatids or 2 homologous chromosomes)
Cell Division vs Nuclear Division
What is cytokinesis?
The actual division of cells into two new cells
This checkpoint checks if all the sister chromatids are correctly attached to the spindle microtubules
M Checkpoint (Spindle Checkpoint)
What is haploid?
- One set of chromosomes (n)
- Gametes or sex cells
- In humans, 23 chromosomes
Mitosis
What happens in metaphase?
- Chromosomes are pulled to the center of the cell
- They line up along the “metaphase plate”