Cell Cycle Flashcards

1
Q

What is the pathway usually taken to get 2 identical daughter cells

A

Binary fission

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2
Q

What is the genetic info composed of in bacterial cells

A

Single circular chromosome

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3
Q

Some cases some prokaryotes have 2 chormosomes what is an example

A

Vibrio cholerae

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4
Q

What does streptomyces have for their DNA

A

Linear chormosome act like a circular one

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5
Q

What is a replicon

A

Portion of chromosome which is able to initiate its own replication

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6
Q

What is the site of initiation

A

OriC origin

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7
Q

Where does termination occur

A

In 100Kb region

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8
Q

What is the period rom initiation to completion of replication

A

Time C (40 mins for ecoli)

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9
Q

What happens to ecoli bidirectional replication

A

Arrests in a termination trap

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10
Q

What is the D time

A

Time after replication to divide (20 mins for ecoli)

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11
Q

How does availability of DnaA protein affect chromosome replication

A

To initiate a new round of DNA replication enough DnaA-ATP has to bind to specific DNA sequences in origin

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12
Q

What do dedicated proteins do

A

Segregate the chromosomes

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13
Q

What do dynamic par proteins do

A

Segregate the chromosomes and plamsids

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14
Q

What is the central event of the cell division

A

The assembly of the FtsZ ring

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15
Q

What effect does FtsZ have on division

A

Controls it

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16
Q

What are the key proteins for cell division

A

FtsZ, FtsI, PBP3

17
Q

In production what happens

A

FtsI encodes PBP3 (penicillin binding protein)

18
Q

What is PBP3

A

Transmembrane protein which cross links peptide side chains

19
Q

What are some factors which are to be considered in prokaryotic growth

A
Food 
Temperature
pH
Osmotic pressure 
Oxygen
20
Q

What is the bacterial cell cycle used for

A

New cell grows in size and splits into 2

21
Q

What is the FTsZ protein

A

First protien to move to site of division

Essential for recruiting other proteins that produce a new cell wall between dividing cell

22
Q

What si the septum

A

Partition that separates the cells of a divide prokaryote

23
Q

What forms the z ring and what does it do

A

Formed from smaller subunits of FtsZ

Filaments pull on each other and tighten to divide the cell

24
Q

What is binary fission

A

Method by which prokaryotic cells produce new individuals that are genetically identical to the parent organism

25
Where is the origin of replication
Close to the binding site of the chromosome at the plasma mem