Cell Cycle Flashcards
PMAT
Prophase, Metaphase, Anaphase, Telophase
Prophase:
Nuclear envelope dissolves, chromatin condenses to form chromosomes
Metaphase
Chromosomes are lined up down center of cell by spindle fibers
Anaphase
Sister Chromatids (double stranded chromosomes) are seperated and pulled to opposite sides of cell (double stranded become single stranded)
Telophase
Cell begins to split creating hourglass shape. Two nuclei form at opposite ends of cell
Cytokinesis
Division of Cytoplasm, everything splits, left w two daughter cells. Part of cell division but not considered part of mitosis.
Interphase
Cell prepares for mitosis, cells spend 90% in this phase. Interphase includes G1 stage, S Stage and G2 stage.
G1
Cell grows and accumulates nutrients
S stage
Synthesis phase, DNA synthesis stage to be specific, replication occurs.
G2
More growth, organelles copied, spindle fibers developed
G1 Checkpoint
Assesses for proper growth and if cell has required nutrients to continue.
G2 Checkpoint
Right before mitosis. Enzymes scan DNA for accurate replication.
Metaphase Checkpoint
Checks for proper spindle fibers attachment.
What happens if a cell fails a Checkpoint?
Cell will attempt to repair the damage, if cell cannot be repaired it will go through Cell Suicide aka Apoptosis
Chromosome
Highly condensed complex of a DNA molecule.