cell cycle Flashcards

(45 cards)

1
Q

what does cell division process allow for?

A

reproduction of cells, growth of cells, and tissue repair

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2
Q

cell cycle

A

the life of a cell from its formation until it divides

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3
Q

what does DNA associate with and weap around when they behin to be packaged before division?

A

proteins known as histones to form nucleosomes

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4
Q

strings of nucleosomes form

A

chromatin

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5
Q

when is chromatin in a non-condensed form?

A

when a cell is not actively dividing

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6
Q

what happens to chromatin after DNA replication?

A

it condensed to form a chromosome

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7
Q

why are cheomosomes densely packed?

A

to allow for easier division

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8
Q

chromosome copied join together to form

A

sister chromatids

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9
Q

centromere

A

region of each sister chromatid where they are most closely attached

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10
Q

kinetochore

A

proteins attached to the centromere that link each sister chromatid to the mitotic spindle

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11
Q

genome

A

all of a cell’s genetic information (DNA)

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12
Q

prokaryotes

A

singular, circular DNA

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13
Q

eukaryotes

A

one or more linear chromosome

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14
Q

homologous chromosomes

A

two chromosomes (one from mom and one from dad) that are the same length, have same centromere position, and carry genes controlling same characteristics

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15
Q

types of cells

A

somatic cells

gametes

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16
Q

somatic cells

A

body cells

diploid (2n): two sets of chromosomes

diviside by mitosis

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17
Q

gametes

A

reproductive cells (eggs/sperm)

haploid (n): one set of chromosomes

divide by meiosis

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18
Q

interphase

A

G1
S
G2

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19
Q

G1

A

“first gap” phase

cell grows and carries out normal functions

20
Q

S

A

“synthesis” phase

DNA replication and chromosome duplication occurs

21
Q

G2

A

“second gap” phase

final growth and preparation for mitosis

22
Q

M phase

A

mitosis: nucleus divides
cytokinesis: cytoplasm divides

mitosis results in 2 identical dipoid daughter cells

23
Q

phases of mitosis

A
1- prophase
2-prometaphase
3- metaphase
4- anaphase
5- telophase and cytokinesis
24
Q

prophase

A

chromatin condenses

nucleoli disappear

duplicated chromosomes appear as sister chromatids

mitotic spindle begins to form

centrosomes move away from each other

25
prometaphase
nuclear envelope fragments microtubules enter nuclear area and some attach to kinetochores
26
metaphase
centrosomes are at opposite poles chromosomes line up at the metaphase plate microtubules are attached to each kinetochore
27
anaphase
sister chromatids separate and move to opposite ends of the cell due to the microtubules shortening cell elongates
28
telophase and cytokinesis
two daughter nuclei form nucleoli reappear chromosomes become less condensed
29
how does cytokinesis occur in animals?
a cleavage furrow appears due to a contractile ring of actin filaments
30
how does cytokinesis occur in plants?
vesicles produced by the golgi travel to the middle of the cell and form a cell plate
31
checkpoints
control points throughout the cell cycle that regulate it (cells receive stop and go signals)
32
G1 checkpoint
checks for cell size, growth factors, and DNA damage GO: cell completes the whole cell cycle STOP: cell eneters a nondividing (quiescent) state known as G0 phase
33
G0
some cells stay in G0 forever (muscle/nerve cells) some cells can be called back into the cell cycle
34
G2 checkpoint
checks for completion of DNA replication and DNA damage GO: cell proceeds to mitosis STOP: cell cycle stops and the cell will attempt to repair damage; if damage cannot be repaired the cell undergoes apoptosis
35
apoptosis
programmed cell death
36
M (spindle) checkpoint
checks for microtubule attachment to chromosomes at kinetochores at metaphase GO: cell proceeds to anaphase and completes mitosis STOP: cell will pause mitosis to allow for spindles to finish attaching to chromosomes
37
internal control system consists of
proteins known as cyclins enzymes known as cyclin-dependent kinases (CDKs)
38
cyclins
concentration of cyclin varies are sysnthesized and degraded at specific stages of cell cycle
39
CDKs
concentration remains constant theough each ohase of cell cycle active only when its specific cyclin is present
40
growth factors
hormones released by cells that stimulate cell growth sugnal transduction pathway is initiated CDKs are activated leading to progression through cell cycle
41
contact (or density) inhibition
cell surface receptors recognize contact with other cells initiated signal transduction pathway that stops cell cycle in G1 phase
42
anchorage dependence
cells rely on attachment to other cells or the extracellular matrix to divide
43
tumor
mass of tissue formed by abnormal cells
44
benign tumor
cells are abnormal, but not considered to be cancerous (yet) cells remain and tumor cite
45
malignant tumor
mass of cancerous cells that lose their anchorage dependency and can leave the tumor cite metastasis: when cells separate from the tumor and spread elsewhere in body