CBL notes 2 Flashcards
Features of metastatic spinal cord compression
- backpain worse on bending and straining
- loss of sensation and motor
- incontinence
- sensory disturbance
Irreversible damage to spinal cord –> Paraplegia
Cancers associated with MSCC
- prostate
- lung
- breast
Management of MSCC
- Call MSCC coordinator
- Log roll
- 16mg dexamethasone stat w/ PPI cover
- Monitor
- blood glucose (steroids can cause hyperglycaemia)
- candida - Radiotherapy or surgery
- bisphosphonates (adjuvant for bone pain)
Features of opioid toxicity:
- extreme drowsiness
- pinpoint pupils
- resp depression
- mycoclonus
SE of opiods
- constipation
- N&V
- agitation
- drowsiness
- pruritus
- dry mouth
- hallucination
Scoring system for TIA
ABCD2
Management of TIA
- referral with in 24 hours
- aspirin 300mg now
- TIA clinic with in 24 hours
Definition of orthostatic hypotension
lying standing blood pressure
drop of more than 10mmHg diastolic
or 20mmHg systolic
Management of a patient with a FALL after hospital
- Falls alarm
- OT / PT input
- Comprehensive geriatric assessment
- Smoking, alcohol, BP
- Management polypharmacy
Comprehensive geriatric assessment
- physical
- socioenconomic / environmental
- functional
- mobility / balance
- psychological
- medication review
- personalised care pain
Important drugs to avoid in the elderly
STOPP criteria
- Anti-histamines
- Doxacosin
- anticholinergic
—–> urinary retention
—–> worsening alzheimers - Zopiclone
Name two frailty scores
- PRISMA 7
- Rockwood
Causes of falls and delerium
Pinch Me
P - pain
I - infection
N - nutrition
C - constipation
H - hydration (dehydration)
M- medication
E- environment
Summarise some causes of thrombocytopenia (5)
- Immune thrombocytopenic purpura
- Thrombotic thrombocytopenic pupura
- ADAMST13 association - Hypersplenism
- increased spleen size
- hyperactive spleen - Disseminated intravascular coagulation
- increased clotting - Haemolytic uraemic syndrome
- acute renal failure in kids
- symptoms
a) microangiopathy
b) thrombocytopenia
c) renal insufficiency
Summarise some oncological emergencies (5)
- Metastatic spinal cord compression
- neutropenic sepsis
- superior vena cava obstruction
- hypercalcaemia
- immune therapy induced colitis
Scoring system for neutropenic sepsis, what number would indicate low risk
MASCC score. < 21 = low risk
treatment of neutropenic sepsis
LOW RISK
1. PO coamoxiclav + ciprofloxacin
OR if pen allergic
2. doxy + cipro
High risk
1. IV TAZ AND GENT
OR
2. meropenem and gent
OR
3. Teicoplanin / cipro and gent
What scores are used to determine disability after stroke
- Modified rankin score
- Rosier score (stroke vs non-stroke)
Total anterior circulation stroke
- hemiparesis / hemi sensory loss
- homonymous hemianopia
- higher cortical dysfunction
———-> speech
———-> perceptual problems
PACS
- either 2/3 of TACs
OR
- higher cortical dysfunction alone
—–> speech
—–> perceptual problems
Lacunar stroke
- ataxia
- hemiparesis / hemisensory / hemisensory motor
- NO HEMIANOPIA
NEED JUST 1
POCS (posterior circulation stroke)
Involves damage to area of brain supplied by posterior circulation
(e.g. cerebellum and brainstem)
- hemianopia
- visual loss (cortical blindness)
- cerebellar dysfunction (vertigo, nystagmus and ataxia)
- diplopia
Ischaemic stroke management
FROM SYMPTOM ONSET
Within 4.5 hrs
- thrombolysis w/ alteplase
—-> IV, give 10% bolus then rest in an infusion over an hour
Within 6 hrs
- thrombectomy
Secondary prevention of stroke
- Start antiplatelet after 2 weeks of aspirin 300mg
Atrial fibrillation?
YES
- then start DOAC
NO
- clopidogrel 75mg
Key investigations in patient with suspected stroke
A-E assessment
Aspirin 300mg
Bloods: FBC, G+S, CRP, coagulation studies
Glucose to rule out stroke mimics
ECG: AF?
CXR: rule out other pathology
Summarise different types of heart block
1st degree = PR prolongation
2nd degree
Mobitz 1 = PR gradually getting longer and longer, drops 1 QRS (Wenckebach)
Mobitz 2 = consistent PR interval duration with intermittently dropped QRS complexes , often a repeating cycle
3rd degree = NO ASSOCIATION between P waves and QRS