CB3 Flashcards
in a 70kg man blood volume is ___
5.6L
in a 70kg man blood takes up ___ % of body weight
7-8
blood is ____% water and ___% solids
78, 22
temp of blood
38 degree celcius
ph of blood
7.35-7.45
2/3 of red marrow is dedicated to ______ and 1/3 is dedicated to _______
leucopoiesis, erythropoiesis
there are 500x more _____ than ____
erythrocytes, leukocytes
all peripheral blood cells are derived from a single ______ stem cell
multipotent
progenitor cells divide to produce (5)
erythrocytes, megakaryocytes, granulocytes, lymphocytes, monocytes
differentiated cells lose their capacity for ______
self renewal
stem cells acct for
0.1
what do erythrocytes leave when they leave the marrow
they lose Cell Adhesion Molecules (CAM’s)
what are CAM’s
they allow cells to leave marrow and enter circulation
haemopoiesis requires growth factors such as (4)
erythropoietin, colony stimulating factors, interleukins, and thrombopoietin
structure of hemoglobin in adults and children
adult = alpha2beta2 children = alpha2gamma2
1/3 of thrombocytes are stores in blood filled spaces in _____
spleen
as the fetus develops, the responibility of erythropoiesis changes from ____ to ____ to ____ to ____
yolk sac, liver, spleen, red bone marrow