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CB > CB3 > Flashcards

CB3 Flashcards

1
Q

in a 70kg man blood volume is ___

A

5.6L

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2
Q

in a 70kg man blood takes up ___ % of body weight

A

7-8

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3
Q

blood is ____% water and ___% solids

A

78, 22

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4
Q

temp of blood

A

38 degree celcius

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5
Q

ph of blood

A

7.35-7.45

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6
Q

2/3 of red marrow is dedicated to ______ and 1/3 is dedicated to _______

A

leucopoiesis, erythropoiesis

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7
Q

there are 500x more _____ than ____

A

erythrocytes, leukocytes

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8
Q

all peripheral blood cells are derived from a single ______ stem cell

A

multipotent

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9
Q

progenitor cells divide to produce (5)

A

erythrocytes, megakaryocytes, granulocytes, lymphocytes, monocytes

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10
Q

differentiated cells lose their capacity for ______

A

self renewal

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11
Q

stem cells acct for

A

0.1

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12
Q

what do erythrocytes leave when they leave the marrow

A

they lose Cell Adhesion Molecules (CAM’s)

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13
Q

what are CAM’s

A

they allow cells to leave marrow and enter circulation

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14
Q

haemopoiesis requires growth factors such as (4)

A

erythropoietin, colony stimulating factors, interleukins, and thrombopoietin

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15
Q

structure of hemoglobin in adults and children

A 
adult = alpha2beta2
children = alpha2gamma2
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16
Q

1/3 of thrombocytes are stores in blood filled spaces in _____

A

spleen

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17
Q

as the fetus develops, the responibility of erythropoiesis changes from ____ to ____ to ____ to ____

A

yolk sac, liver, spleen, red bone marrow

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18
Q

process in adults from stem cell to erythrocyte

A

stem cell/hemocytoblast - proerythroblast - early erythroblast - late erythroblast - normoblast - reticulocyte - erythrocyte

19
Q

1 proerythroblast turns into how many RBC’s

20
Q

RBC’s are replaced at an avg rate of ______ million cells per second

21
Q

haemoglobin components, such as globin, iron, and heme, can be ______

22
Q

what nutritional aspects affect the maturation and production of RBC’s

A

aa’s, vitamins (b12 and folate), and iron

23
Q

______ is one of the most commonly ordered laboratory tests

A

full blood count, complete blood count

24
Q

FBC/CBC measures ____ cell counts

A

RBC, WBC, and platelets

25
Q

forumla for RBC count =

A

(4-5-5.4) x 10^6 /mL

or

(4-5-5.4) x 10^12/mL

26
Q

reticulocytes % should equal

27
Q

packed cell volume measures the fraction of blood occupied by ____

A

erythrocytes

28
Q

packed cell volume should be ____ %

29
Q

hemoglobin should be __-__ g/dL in males and ___-___ g/dL in females

A

14,18,12,16

30
Q

the amt of Hb in blood is an indicator of _____ binding capacity

31
Q

what does it mean if the mean cell volume is high

A

the size of red blood cells is high

32
Q

mean cell heamoglobin measures the _____

A

avg amt of hemoglobin in a RBC

33
Q

mean cell hemoglobin concentration is the _____

A

amt of hemoglobin per dL RBC

34
Q

range of Mean cell volume =

35
Q

range of mean cell Hb

36
Q

range of MCHC

A

32-35 g/dL

37
Q

clinical signs of anemia

A

fatigue and weakness, pallor, koilonychia, angular stomatitis, glossitis

38
Q

what is pallor

39
Q

what is koilonychia

A

nail curves upward (spoon shaped)

40
Q

what is angular stomatitis

A

deep cracks and splits at corner of mouth

41
Q

what is glossitis

A

inflammation/infection of tongue

42
Q

what is included in a basic clinical evaluation

A

review of blood count/blood smear, RBC indices, reticulocyte index, and determination of short term/long term

43
Q

what are the 2 types of hypochromic-microcytic anaemia

A

iron deficiency and STOPPED AT SLIDE 32 CB3

CB (10 decks)

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