causes of brain dysfunction Flashcards

1
Q

types of open head injuries

A

penetrating and perforating

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2
Q

types of hematomas from contusion

A

epidural, subdural, intracranial

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3
Q

contusion

A

occurs by brain slamming against the skull, producing internal hemorrhaging and a resultant hematoma

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4
Q

types of closed head injuries

A

coup & coup countrecoup

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5
Q

concussion

A

mTBI - no evidence of contusion or other structural damage; collection of symptoms

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6
Q

Tumour

A

abnormal cell growth; usually white matter cells

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7
Q

encapsulated tumor

A

inside membrane, single mass growing slowly. Benign. Small chance of growing back

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8
Q

Meningioma

A

encapsulated tumor between meninges

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9
Q

infiltrating tumor

A

grows through surrounding brain tissue, woven in with healthy tissue. Malignant. High chance of reoccurring.

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10
Q

metastatic tumor

A

started somewhere else and carried to the brain, growing as infiltrating tumor.

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11
Q

glioblastoma

A

most common type of malignant brain tumor. Most malignant.

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12
Q

infarct

A

dead area following stroke, within 4 minutes

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13
Q

penumbra

A

nearby regions with disrupted blood flow. Neurons may live or die in following 2 weeks. Major goal is saving penumbra

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14
Q

Types of stroke

A

ischemic & hemorrhagic

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15
Q

Ischemic stroke

A

disruption of blood supply to some brain area due to blockage

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16
Q

Hemorrhagic stroke

A

generally worse (loss of blood supply + blood is toxic for brain).

17
Q

aneurism

A

stretch on artery, creating blood balloon that may rupture. Common factor of aging

18
Q

Treatment for aneurysm

A

clipping & endovascular coiling

19
Q

3 main causes of cerebral ischemia

A

thrombosis, embolism, arteriosclerosis

20
Q

Apoptosis

A

programmed cell death from too much calcium

21
Q

Chronic traumatic encephalopathy (CTE)

A

progressive, irreversible diminished cognitive ability. caused by repeated blows to the head (even w/o concussion)

22
Q

Taupathies

A

CTE, Alzheimers, Parkinsons

23
Q

encephalitis

A

inflammation of the brain

24
Q

cerebral abscesses

A

pus pockets from bacteria

25
meningitis
inflammation of the meninges
26
general paresis
psychosis/dementia developed due to syphilis in the brain
27
rabies mechanism
travel backwards up motor neurons to the spinal cord, and then brain
28
Neurocysticercosis
worm in the brain
29
toxic psychosis
psychosis/dementia due to mercury poisoning
30
Minamata disease
methylmercury poisoning
31
crackpots
related to lead exposure
32
MadHatter
related to mercury exposure
33
forms of MS
relapsing-remitting, secondary progressive, primary progressive
34
MS outside-in theory
primarily an autoimmune disorder
35
MS inside-out theory
primarily a neurodegenerative disorder
36
geographical differences in incidence rates of MS suggest...
relationship of MS with (low) vitamin D, especially in the first 15y. higher risk for white ppl
37
strengths of Bjornevik et al. 2022 study on Epstein-Barr virus and MS
longitudinal; MS only developed after exposure to EBV (800 in 801) - huge risk factor.
38