Case 7- seminar recources Flashcards
List 3 bacterial causes of RTI
Streptococcus pneumoniae
Staphylococcus aureus
Haemophilus influenzae
List 3 viral causes of RTI
RSV
Influenza (A,B C)
Adenovirus
List 3 fungal causes of RTI
Candida spp.
Aspergillus spp.
Mucor spp.
Definition of community acquired pneumonia
Signs and symptoms of acute lower respiratory tract infection with radiographic shadowing with no other explanation. This must have occurred in the community setting. If the symptoms develop after 48 hours in hospital, it is hospital acquired pneumonia
The causative agent of CAP
Streptococcus pneumoniae
The bacteria associated with pneumonia secondary to infection
Staphylococcus aureus
How many people under 5 die from pneumonia
About 1 million
Type of pneumonia associated with poorly decontaminated cooling towers
Legionella spp.
What can NSAID’s cover
A fever
Example of immunosuppressant
Methotrexate
Effect of immunosuppressants on lungs
Can cause fibrosis in the lungs, leaves them more open to infection
What proportion of adult sore throats are caused by virus’s
85-90%
What is the major cause of bacterial sore throat
(GAHBS) also known as Streptococcus pyogenes
Two bacteria commonly associated with hospital acquired pneumonia
E.coli, S.aureus, Klebsiella spp
A fungal infection associated with HIV related pneumonia
Pneumocystis jirovecii (previously P.carinii)
An antibiotic empirically used to treat CAP
Amoxicillin, if allergic to penicillin Clarithromycin (erythromycin if pregnant)
The virus that causes the majority of bronchiolitis in children under 1
RSV
How effective is the flu vaccine
10-30%
Cause of Pharyngitis
Bacteria= Streptococcus pyogens Virus= Adenovirus, Coxsackevirus
Cause of Sinusitis
Bacteria= Streptococcus pneumoniae, Haemophilus influenzae
Cause of Epiglottis
Bacteria= Haemophilus influenzae, β-haemolytic streptococci (groups A, B, and C)
Virus- Staph.a, Streptococcus pneumoniae.
What causes a sore throat
Due to an acute upper respiratory tract infection which affects the mucosa of the throat
Pathogens which cause a throat infection
Virus- rhinovirus, coronavirus, influenza A and B.
Bacteria- Group A BH Strep (GAHBS)
Fungal- Candida Albicans
FeverPAIN criteria, the likelihood of a soar throat being Streptococcus
0 or 1 - 13to 18% likelihood of isolating streptococcus
2 or 3 - 34to 40% likelihood of isolating streptococcus
4 or 5 - 62to 65% likelihood of isolating streptococcus
If over 5 immediately prescribe antibiotics
Epiglottitis
Inflammation of the epiglottis. Presents with sore throat, stridor in children. People tend to get it between 2-5.
Diptheria
Caused by Corynrbacterium diptheriae which is a gram +ve rod. Fatality rate between 10-15%. Cases rapidly dropped once the vaccine was introduced. It forms a grey exudate (pseudomembrane) which can block the throat leading to infection
Mechanism of c.diphtheriae
The disease is caused by the release of a single exotoxin. The toxin inhibits cell protein synthesis leading to tissue destruction. The toxins produced in the Pseudomembrane enters the bloodstream and causes damage to distant sites. Complications- death, Myocarditis and Neuritis (inflammation of nerves).
Treatment of C.diphtheriae
Treatment with antitoxins, antibiotics including Penicillin G and Erythromycin.
Cause of Croup
Parainfluenza
Symptoms of Croup
Occurs in childhood, causes a harsh barking cough, hoarse voice and inspiratory stridor. Normally occurs in children younger then 3
Whooping cough
Caused by the bacterium Bordetella Pertussis, spread by aerosol droplets. It is a protracted cough which follows a pertussis infection. Affects infants and young people. The cough lasts for 3 months or more. There is a vaccine against it
Whooping cough disease pattern
The catarrhal phaselasts between one and twoweeks. Symptoms similar to general URTI
The paroxysmal phasetypically occurs about 1 week after the catarrhal phase and lasts between one and six weeks. Between coughing fits (paroxysms), the person is usually relatively well
The convalescent phaselasts up to 3 months with gradual improvement in cough frequency and severity
6 in 1 vaccination
1) Diptheria
2) Hepatitis B
3) Hib
4) Polio
5) Tetanus
6) Whooping cough (pertussis)
When do you get the 6 in 1 vaccination
Its given at 8, 12 and 16 weeks