Cartilage and Bone Flashcards

1
Q

Cartilage functions?

A

Soft tissue support.
Articulations: Smooth surfaces where bones meet.
Precursor model for bone growth.

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2
Q

Cartilage characteristics?

A

Semi-rigid connective tissue, mature cartilage is avascular.

Cells of cartilage: Chondroblast- Young cells that produce matrix, Chondrocytes-Older cells, surrounded by matrix

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3
Q

Makeup of cartilage?

A

Cells and extracellular matrix. (Its a from of connective tissue)

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4
Q

3 Types of cartilage?

A

Hyaline cartilage
Elastic cartilage
Fibrocartilage

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5
Q

Hyaline cartilage characteristics?

A

Most common type, also weakest. Glassy texture. Lacks significant collagen. Found at end of bones that articulate.

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6
Q

Elastic Cartilage characteristics?

A

contains mainly elastic fibers and chondrocytes. Both structures need to bend and snap back to original form.

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7
Q

Fibrocartilage Characteristics?

A

Densely interwoven collagen fibers contribute to durability. Found in knee meniscus. Acts as shock absorber, resists tension in one direction.

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8
Q

Characteristics of bones?

A

Contains all four tissue types. Primarily CT. Extracellular matrix is sturdy and rigid. Strengthened by calcification.

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9
Q

What is calcification

A

Minerals are deposited in matrix of bones. Main storage and source of Ca and PO4 ions.

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10
Q

Bone function?

A
Support.
Protection
Anchors for movement
Hematopoiesis: Blood cell production
Storage.
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11
Q

Bone classification?

A

Long bones: Greater length than width.
Short bones: Nearly equal length and width.
Flat bones: Thin surfaces
Irregular bones: Complex shapes.

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12
Q

Long bone characteristics?

A

Have compact and spongy bone. Longer than wide. Most common type of bone.

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13
Q

Short bone characteristics?

A

Have compact and spongy bone. Roughly equal with and length.

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14
Q

Flat bone characteristics?

A

Compact and spongy bone. Provide muscle attachment sites. Protect underlying structures.

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15
Q

Irregular bone characteristics?

A

Oddly shaped, does not fit into any regular category.

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16
Q

Long bone anatomy?

A

Diaphysis: Shaft
Epiphysis: Knobby enlarged end regions.
Metaphysis: Between diaphysis and epiphysis. Contains epiphysial (growth) plate.
Articular cartilage: Thin layer of hyaline cartilage on epiphyses.
Medullary/marrow cavity: space in shaft. Usually contains yellow bone marrow.

17
Q

Bone coverings?

A

Periostuem: Dense irregular connective tissue. Covers external bone surfaces. Doesnt cover articular cartilage. Blood vessel and nerve anchors. Anchored by Sharoey fibers in bone matrix.
Endosteum: Covers most internal bone surfaces.

18
Q

Cells of bone?

A

Osteoprogenitors: Stem cells, found inendosteum and periosteum. produce more stem cells or osteoblasts.
Osteoblasts: Young matrix forming cells, very mitotic.
Osteocytes: Mature cells that reside in lacunae, maintain matrix and communicate with osteoblast for more bone matrix deposit.
Osteoclasts: Large multinucleate cells that dissolve cartilage and bone releasing Ca2+ ions.

19
Q

Bone matrix?

A

1/3 organic components and 2/3 inorganic components.

20
Q

Compact bone?

A

Aka. cortical bone. Solid and dense, external surfaces of long and flat bones.

21
Q

Spongy bone?

A

Aka cancellous or trabecular bone. Open lattice of narrow plates called trabeculae. Internal surface of bones

22
Q

Osteon characteristics?

A

Basic structural and functional unit of mature compact bone. AKA haversian system. Cylindrical. Parallel to bone shaft.

23
Q

Osteon components?

A

Lamellae

Canals

24
Q

Characteristics of osteon lamellae?

A

Concentric lamellae: Rings of bone around central canal.
Circumferential lamellae: Along outer edge under periosteum.
Interstitial lamellae: leftover old osteon.

25
Characteristics of osteon canals?
Central (haversian) canal: Carries blood vessles and nerves. | Perforating (Volkmanns's) canal: Perpendicular connections to central canal with blood vessels and nerves.
26
What is ossification? What are the types of ossification?
Formation and development of bone. Two general forms: Intramembranous and endochondral.
27
Intramembranous ossification?
Develops from mesencyme. Produces flat skull bones, some facial bones, mandible and centra portion of clavicle.
28
Endochondral ossification?
Begins with a hyaline cartilage model. Produces majority of bones in body.
29
Types of bone growth?
Appositional: Increases bone diamter. Interstitial: Increase bone length.
30
Epiphyseal (growth) plate vs. Epiphyseal (growth) line?
Epiphyseal plate: Cartilage, still growing.Appears as dark gap on X-ray. Epiphyseal line: Ossified bone, appears as white band on X-ray.