Carotenoids Flashcards

1
Q

what are the three most common dietary provitamin A carotenoids

A
  1. alpha - carotene
  2. beta - carotene
  3. beta - cryptoxanthine
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2
Q

what carotenoid is physiologically important

A

lycopene

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3
Q

oranges, tangerines, and red bell peppers provide

A

beta - cyptoxanthine

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4
Q

egg yolks are a rich source of

A
  1. lutein

2. zeaxanthin

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5
Q

_____ protects carotenoids from oxidation

A

vitamin E

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6
Q

too much vitamin E can diminish carotenoid absorption

A

T

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7
Q

in the enterocyte, beta - carotene is cleaved by using

A

beta - carotene 15,15’ - monoxygenase

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8
Q

________ transcriptional expression is suppressed when retinoic acid concentrations gets too high

A

beta - carotene 15,15’ - monoxygenase

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9
Q

what are the 3 routes of metabolism of carotenoids

A
  1. cleaved and reduced to form retinol
    • packaged and released from the liver in VLDL’s *
  2. stored in the liver’s stellate cells
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10
Q

in the serum, carotenoids are transported using

A

VLDLs, LDLs, and HDLs

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11
Q

what is the best carotenoid free radical scavenger

A

lycopene

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12
Q

____ appears more effective in inhibiting neoplastic transformations than beta - carotene followed by alpha - carotene, and then lycopene

A

canthaxanthin

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13
Q

carotenoids suppress anti-apoptotic genes in cancer cells and activates pro-apoptiotic genes

A

T, inhibits 5 alpha - reductase

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14
Q

what immune enhancing functions do carotenoids provide

A
  1. increased lymphocytes
  2. enhanced natural killer cell cytotoxicity
  3. stimulated neutrophil phagocytic and bacterial killing ability
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15
Q

beta - carotene supplementation can increase cancer risk in smokers, asbestos workers, and chronic alcoholics

A

T

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