care of infants and pediatrics review

Question 1

what complicates the med process for infants and peds

Answer 1

variables in absorption, distribution, metabolism, and excretion

Question 2

how is infant/pediatric dosing based

Answer 2

mainly weight based

Question 3

name some factors affecting older adult pharmacodynamics

Answer 3

• rduced receptor sites
• med tolerance
• chronic illness
• polypharmacy

Question 4

what is beers criteria

Answer 4

lists meds that may be inappropriate for older adults

Question 5

effects of physiological changes on pharmacokinetics in old ppl

absorption

Answer 5

-increased gastric pH
-delayed gastric emptying
-decreased blood flow
-decreased intestinal mobility

Question 6

effects of physiological changes on pharmacokinetics in old ppl

distribution

Answer 6

-increased body fat
-decreased total body water
-decreased serum albumin
-cerebral flow

Question 7

effects of physiological changes on pharmacokinetics in old ppl

metabolism

Answer 7

-decreased hepatic mass
-decreased other shit

Question 8

effects of physiological changes on pharmacokinetics in old ppl

elimination

Answer 8

-decreased GFR
-decreased tubular filtration
-creatinine