Cards Flashcards

1
Q

What electrolyte disorder is common in myleoma

A

hypercalcaemia

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2
Q

what are the presenting features of myeloma

A

Older adults - median age 60 years; male more than female
Anaemia
Bone pain - most common in the back or ribs; may present as a pathologic fracture following minimal trauma, especially of the femoral neck
Infection - commonly with encapsulated organisms such as Streptococcus pneumoniae, Haemophilus influenzae; due to suppression of antibody production and neutropenia
Hypercalcaemia - nausea, fatigue, confusion, polyuria, constipation
Weight loss is common
Hyperviscosity.

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3
Q

What is a common cause of post operative foot drop

A

pressure on the common peroneal nerve during anaesthesia

ensure padding on the fibula head during operations

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4
Q

why is a central neurological cause unlikely to result in foot drop

A

would not cause a well defined peripheral nerve lesion

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5
Q

give common causes of hypercalcaemia

A
primary hyperparathyroidism 
hypercalcaemia of malignancy 
paraneoplastic syndrome
lymphoma 
thyrotoxicosis
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6
Q

what blood features might you find in severe boughts of prolonged vomiting

A

high serum aldosterone
hypochlorydia
hypokalaemia
tetany (caused by metabolic acidosis)

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7
Q

would you expect high or low bicarb in a metabolic acidosis

A

low (this is not compensation)

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8
Q

what are the functions of aldosterone

A

steroid hormone that retains sodium

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9
Q

what is the opposite of aldosterone

A

atrial naturetic peptide

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10
Q

what is a strain pattern on an ECG?

A

left ventricular hypertrophy
large voltages in the chest leads
ST depression and T wave inversion

with hypertension suggests end organ damage

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11
Q

what is the inheritance pattern of haemophillia A

A

X linked recessive

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12
Q

will the son of a haemophilliac have haemophillia

A

no because they inherit the X chromosome from their mother

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13
Q

what artery originates from the left posterior aortic sinus

A

left coronary artery

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14
Q

what artery supplies the AV node

A

right coronary artery

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15
Q

what vessel opens into the right atrium

A

coronary sinus

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16
Q

what artery supplies the apex of the heart

A

LAD

17
Q

what artery lies in the anterior atrioventricular groove

A

right coronary artery

18
Q

what artery runs in the posterior AV groove

A

circumflex

19
Q

what are the commonest causes of optic atrophy

A
glaucoma 
MS
compression due to aneurysms
Pagets disease
tumours
20
Q

what conditions are associated with blue sclerae

A
osteogenesis imperfecta
ehlers danlos syndrome
marfans syndrome
chronic corticosteroid use
Fe deficiency anaemia 

due to underlying choroidal veins showing through the thin sclera

21
Q

what is cushings disease

A

pituitary dependent cushings syndrome

22
Q

what are the features of TTP

A

pupura, fever, haemolytic anaemia, microvascular thrombosis, renal failure, mild stroke, fragmented red cells

23
Q

what can cause TTP

A
cytotoxic drugs
SLE
pregnancy 
oral contraceptive use 
usually no known cause
24
Q

what is haemolytic uraemic syndrome

A

haemolytic anaemia
acute kidney failure
thrombocytopaenia

25
Q

what are the features of scurvy

A
occurs in people with poor nutrition 
perifollicular skin bleeding
prolonged bleeding time 
vit C deficiency 
weakness
tiredness
sore arms and legs 
gum disease
hair changes
26
Q

what are features of EDS

A
abnormal velvety hyperelastic skin 
poor skin healing
hyperextensible joints
purpura
psuedotumours from organisations of haematomas from injuries 
hydrarthrosis
repeated falls
27
Q

what is henloch schonlein pupura

A
arthritis 
colicky abdo pain 
arthritis
polyarthritis
purpura
melaena
haematemesis
obstruction 
intussusception 
glomerulonephritis
28
Q

what investigation should you give patients on warfarin with a history of a loss of consciousness

A

CT head

29
Q

what is a mallory weiss tear

A

occurs following episodes of vomiting following alcohol or gastroenteritis
they require no intervention

30
Q

how can you lower portal pressure

A

beta blockers

31
Q

what can cause a small pupil

A
horners syndrome
old age
pontine haemorrhage
argyll robertson pupil 
drugs
opiates
32
Q

what causes dilated pupils

A
holmes adie pupil
third nerve palsy
drugs 
atropine 
CO 
ethylene glycol
33
Q

what is a holmes adie pupul

A

dilated pupil that reacts more to accomodation than light

infection to cilliary ganglion (psymp)

34
Q

what are the features of turners syndrom

A
abnormal breast development 
coarctation of the aorta
increased incidence of bone fractures
infantile lymphodema
primary amenorrhoea
hypertension 
facies
fold of skin on neck 
elbow deformity 
brown nevi
widely spaced nipples
shield shaped thorax
low hairline 
webbing of neck