Cardiovascluar Flashcards

1
Q

hypertension drugs

A

diuretics (furosemide)
beta blockers (propanolol)(metoprololor)
alpha 1 blockers (prazosin)
centrally acting adrenergics (methlydopa/clonidine)
neuronal blockers (guanethidine)(severe hypertension)
ACE inhibitors (lisinopril)

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2
Q

cardioselective beta blocker

A

metoprololor atenolol

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3
Q

angina drugs

A

nitro
propanolol
Calcium channel blockers (verapamil)

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4
Q

arrhythmia drugs

A
lido 
phenytoin
quinidine
verapamil
digitalis
propanolol
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5
Q

what type of arrhythmia does lido help?

A

VENTRICULAR

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6
Q

what type of arrhythmia does phenytoin help?

A

digitalis induced

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7
Q

what type of arrhythmia does quinidine help?

A

SUPRAventricular tachy

ATRIAL fillibration

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8
Q

what type of arrhythmia verapamil help?

A
SUPRAvetricular tachy
ATRIAL fillibration (same as quinidine)
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9
Q

what type of arrhythmia does digitalias help?

A

ATRIAL fillibration

paraxysmal tachy

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10
Q

what type of arrhythmia does propanolol help?

A

paraxysmal tachy

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11
Q

what drugs help congestive heart failure?

A

gylcosides such as:

digitalis
digoxin
ACE inhibitors (captopril)

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12
Q

how does quinidine act for antiarryhthmics?

A

type 1A agent that acts by inc the refractory period of cardiac muscle

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13
Q

how does lido act for antiarrythmics?

A

type 1B agent that dec cardiac excitability

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14
Q

how does digitalis act for antiarrhythmics?

A

dec the rate of A-V conduciton

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15
Q

how does nitro work as an antiangina drug?

A

inc O2 supple to heart by a direct vasodilatory action on smooth mm in coronary ateries

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16
Q

how does propanolol work as an antiangina drug?

A

reduces O2 demand by preventing chronotropic responses to endogenous epi, emotions, and excercise

17
Q

how does Calcium Channel Blockers work as antiangina drug?

A

dec O2 demand by reducing afterload by reducing peripheral resistance via vasodilation

18
Q

generally, how do most antihypertensives work?

A

reducing peripheral resistance via vasodilation

19
Q

how does the antidiuretic ACE inhibiotors work?

A

blocks the enzyme which converts angiotension I to angiotension II. the latter is a potent vasoconstrictor

20
Q

what are the adrenergic agents?

A
prazosin
methyldopa
clonidine
propanolol
metoprolol
21
Q

how does adrenergic agent prazosin work?

A

selective alpha1 blocker, inhibits binding of nerve induced release of NE resulting in vasodilation

22
Q

how does adrenergic agent methyldopa work?

A

acts centrally as a false neurotransmitter stimulating alpha receptors to reduce sympathetic outflow resulting in vasodilation

23
Q

how does adrenergic agent clonidine work?

A

selective agonist stimulates alpha-2 receptors in the CNS to reduce sympathetic outflow to peripheral vessels resulting in vasodilation

24
Q

how does adrenergic agent propanolol work?

A

nonselective beta blocker reduces cardiac output and inhibits renin secretion

25
how does adrenergic agent metoprolol work?
selective beta 1 blocker, reduces cardiac output
26
how do diuretics work?
dec the renal absorption of sodium, thus resulting in fluid loss and a reduciton in blood volume, this dec the work the heart has to pump, also they have a weak dilatory action
27
three types of diuretics
thiazide: chlorothiazide furosemide (loop acting) potassium sparing (spironolactone)
28
how do congestive heart failure drugs (digitalis, digoxin) work?
have positive ionotropic effect, inc the force of contraction. this is done by an inhibition of Na+, K+ ATPase leading to inc calcium influx. digitalis reduces compensatory changes such as inc heart size, rate, and edema