Cardiotonics: Heart Failure Treatments Flashcards
What is the definition of heart failure?
Condition in which the heart fails to effectively pump blood throughout the body
What does the primary treatment of heart failure do?
It allows the heart muscle to contract more efficiently in an effort to bring the system back into balance.
What are the 4 causes of congestive heart failure?
Dysfunction of the cardiac muscle caused by:
- Coronary Artery Disease (CAD)
- Cardiomyopathy
- Hypertension
- Valvular Heart Disease
Heart muscle damage is typically caused by what two things?
- Atherosclerosis
- Cardiomyopathy
Increase in workload to maintain an efficient output can be caused by what two things?
- Hypertension
- Valvular disease
A structural abnormality of the heart is typically caused by:
Congenital cardiac defects
What are the three underlying problems in heart failure involving muscle function?
- Muscle damage
- Increase in workload to maintain an efficient output
- Structural Abnormality
What is the sarcomere composed of?
Protein fibers
- Thin actin fibers
- Thick myosin fibers
What are the two compensatory mechanisms?
Decreased cardiac output
Cellular changes
Decreased Cardiac Output is due because of these two things?
Sympathetic stimulation and release of renin
What are the three types of cardiotonic (inotropic) drugs?
- Cardiac glycosides
- Phosphodiesterase inhibitors
- HCN Blockers
What do cardiac glycosides increase?
Increase the force of myocardial contraction, cardiac output, and renal perfusion.
What do cardiac glycosides decrease?
Decreases blood volume to slow heart rate and conduction velocity through the AV node.
What is the indications that a patient needs to be prescribed cardiac glycosides?
Treatment of:
Heart Failure
Atrial fibrillation
What are the adverse effects associated with cardiac glycosides?
- Headache, weakness, drowsiness, and vision changes.
- GI upset and anorexia
- Arrhythmia development