Adrenergic Agents Flashcards

1
Q

Beta-Adrenergic Blocking Agents do what?

A

Competitive blocking of the beta-receptors in the SNS

Blocking of beta receptors in the heart and juxtaglomerular apparatus of the nephron

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2
Q

What are the indications for beta-adrenergic blocking agents?

A

Treating:
Cardiovascular problems, hypertension, angina, and migraine headaches
Preventing:
Reinfarction after MI

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3
Q

What are the contraindications of prescribing beta-adrenergic blocking agents?

A
  • Diabetes
  • Bradycardia
  • Heart block
  • Shock
  • CHF
  • COPD
  • Asthma
  • Pregnancy and lactation
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4
Q

What two things would cause a prescriber to use caution when prescribing beta-adrenergic blocking agents?

A

Diabetes

Hepatic dysfunction

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5
Q

What are the adverse reactions associated with beta-adrenergic blocking agents?

A
  • Fatigue, dizziness, depression, sleep disturbances
  • Bradycardia, heart block, hypotension
  • Nausea, vomiting, diarrhea
  • Decrease libido
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6
Q

What drugs interact with beta-adrenergic blocking agents?

A

Clonidine
NSAIDs
Insulin or anti diabetic medications

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7
Q

What is the prototype drug for beta-adrenergic blocking agents?

A

Propranolol

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8
Q

What is the advantage of beta 1 selective adrenergic blocking agents?

A

They do not usually block beta 2 receptor sites including the sympathetic bronchodilation

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9
Q

What is the indication that a patient should be put on beta 1 selective adrenergic blocking agents?

A

Hypertension
Angina
Some cardiac arrhythmias

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10
Q

Who is the preferred patient to be prescribed beta 1 selective adrenergic blocking agents?

A

Those who smoke, have asthma, obstructive pulmonary disease, or seasonal allergic rhinitis.

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11
Q

What are the contraindications for prescribing beta 1 selective adrenergic blocking agents?

A
Sinus bradycardia
Heart block
Cardiogenic shock
CHF
Hypotension
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12
Q

When should a prescriber use caution when prescribing beta 1 selective adrenergic blocking agents?

A

COPD
Diabetes
Thyroid disease

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13
Q

What drugs have interactions with beta 1 selective adrenergic blocking agents?

A

NSAIDs

IV lidocaine

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14
Q

What is the prototype for beta 1 selective adrenergic blocking agents?

A

Atenolol

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15
Q

What are the adverse effects associated with atenolol?

A
Dizziness
Bradycardia
Heart Failure
Arrhythmias
Gastric pain
Flatulence
Impotence
Bronchospasm
Decreased exercise tolerance
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