Cardiology Flashcards
Essential hypertension stages
- Normal: < 120/80 or < 0th percentile for age/height
- Elevated: 120/80 - 129/80 or between 90-95th percentiles
- Stage 1: 130/80 - 139/89 or > 95th percentile + 12 mm Hg
- Stage 2: > 140/90 or > 95th + 12 mm Hg
Essential hypertension workup/initial management
- Start with lifestyle modifications and recheck in 3 months.
- If still elevated, do ambulatory BP monitoring followed by investigation of cause and then treatment
- Initial workup is often UA, electrolytes, 4 extremity pulse/BP
Infective endocarditis organisms
Staph aureus for native valve, strep viridans for abnormal valves (CHD, rheumatic heart disease, etc).
Others: AACEK (Kingella)
Infective endocarditis symptoms
FROM JANE: Fever Roth spots (retinal hemorrhages) Osler's nodes (painful nodules on toes/fingers) Murmur Janeway lesions (painless hemorrhagic lesions on palms/soles) Anemia Nail hemorrhage Emboli
Duke criteria - need 2 major, 1 major and 3 minor, or 5 minor
Major:
- Positive blood culture with typical organism
- Echo consistent with endocarditis
Minor:
- Predisposing heart condition
- Fever
- Vascular phenomena
- Immunological phenomena
- microbiological evidence (positive culture but not consistent with IE organism)
Causes of hypertension
- Polycystic kidney disease
- 11 hydroxylase deficiency
- Urinary reflux nephropathy
- Renal artery stenosis
- Neurofibromatosis
- 17 hydroxylase deficiency
- Coarctation
- Pheochromocytoma
- Lupus/rheum disorders
- Cushings
- Hyperthyroidism
- Drugs: albuterol, OCPs, steroids, decongestants, illicit drugs
Family history of hypertension cause hint
- Renal or endocrine problems that run in the family
Prematurity cause hint of hypertension
Renal artery stenosis secondary to umbilical catheterization
Joint pain/swelling cause hint of hypertension
Lupus
Flushing, palpitations, fever, weight loss cause hint of hypertension
Pheochromocytoma
Muscle craps, weakness cause hint of hypertension
Hyperaldosternoism
Onset with sexual development cause hint of hypertension
Enzyme deficiencies
Pharmacological management of hypertension
- CCBs: nifedipine or amlodipine
- Vasodilators: hydralazine
- ACEIs: lisinopril or enalapril
- ARBs: losartan
- Beta blockers: propranolol or atenolol
- Alpha 2 agonists: clonidine
- Diuretics: thiazides, furosemide, spironolactone
Rheumatic fever diagnostic criteria
2 major OR 1 major plus 2 minor with evidence of GAS infection
Major: JONES
- Joints (polyarthritis)
- Heart (carditis)
- Nodules (subq)
- Erythema marginatum
- Sydenham chorea (emotional lability with rapid movements of extremities - this is enough to diagnose RF alone)
Minor
- Fever > 38.5
- Arthralgia
- Elevated ESR or CRP
- Prolonged PR interval
Percentage of kids that will have a murmur at some point
90% of kids will have a murmur at some point in their life and only 5% are pathologic
Normal variant of 3rd heart sound
If child is lying down it could be normal, it will go away when they sit up if it’s benign
Fixed split second heart sound, decreased exercise tolerance, murmur at left upper sternal border
ASD
- Murmur is from relative increase in flow through the pulmonary valve (relative pulmonic stenosis)
- If ASD is missed it could lead to Eisenmenger syndrome (right to left flow due to PH and blue kid)
Blowing/harsh holosystolic murmur at left lower sternal border
VSD
- Bigger the VSD = quieter murmur but more symptoms
Systolic (ejection) click that varies with respiration, normal splitting S2 with murmur at LUSB
Pulmonary stenosis
- Often have RVH
- Can also have a thrill and it can radiate to the back
Systolic (ejection) click heard at the apex that does NOT vary with respiration, murmur heard best at RUSB
Aortic stenosis
- Often have LVH
To and fro or continuous machine murmur
PDA
Stills murmur vs venous hum
- Venous hum is vibratory/musical and disappears with pressure on jugular vein
- Stills murmur will be louder supine and softer on standing
Association with right sided aortic arch
22q11 deletion
Left axis deviation without LVH
Tricuspid atresia and AV canal defects (due to effect on conduction system)
LVH without left axis deviation
Hypertrophic cardiomyopathy
CCHD screening guidelines
- Passing is 94-96%
- Repeat screening can limit false positives for PDA
- Most reliable after 24 hours of age
- Greater sensitivity is achieved with pulse ox on right hand (pre-ductal) compared to pulse ox on a foot (post-ductal)
Systolic murmur in left axilla with radiation to back, can have early diastolic component
Coarctation
- Have systolic hypertension and decreased pulses in lower extremities
- Coarc in a neonate presents with RVH because RV is pumping chamber in fetus