Cardio/Lipid Pharm Flashcards
1
Q
Drug that inhibits Mevalonate. Toxicities?
A
Statins. Hepatotoxicit and rhabdomyolysis/myocities.
2
Q
Drug to raise HDL. Mechanisms?
A
Niacin.
1) Inhibit lipolysis
2) reduce VLDL secretion
3
Q
Pt comes in with flushing, acanthosis nigracans, and an exacerbation of gout. what drug is he on?
A
Niacin
4
Q
Drug that will lower LDL but raise cholesterol?
A
Bile acid resins (Cholestryamin, colestipol, colesevelam)
5
Q
Ezetimibe?
A
Blocks cholesterol resorption in gut
6
Q
These drugs make lead to gallstones from blocking this enzyme?Other toxicities?
A
Fimbrates. Supress 7a-hydroxylase. Myositis/hepatoxicities.
7
Q
High TG. Give what? then what?
A
Fibrate then add Niacin
8
Q
High LDL. Give what. then what?
A
Statin then ezetimbe
