Autonomic Pharm Flashcards
cholinomimetic used for Ileus and urinary retention
Bethanechol
Used for glaucoma as a topical and used for cataract surgery
Carbachol
Increases sweat, tear and saliva
pilocarpine
Challege test for asthma
methacholine
Stimulates only Muscarinic Receptors?
Bethanechol and Methacholine
Stimulates both Muscarinic and nicotinic receptors
Carbachol, pilocarpine
anticholinesterase used to ileus and urinar retention. Cannot penetrate CNS
neostigmine
Used for myasthenia gravis?
Pyridostigmine, neostigmine
Used to dx myasthenia gravis?
edrophonium
Used for atropine OD. Crosses BBB
physostigmine
anticholinesterase used for ALZ disease
donepezil
drugs that cause exacerbation of COPD, asthma, and peptic ulcers?
Cholinomimetics
Too much ACh. Sx?
DUMBBELSS
Diarrhea, urination, miosis, bradycardia, bronchospasm, excitation of skeletal muscle, Lacrimation, salivation, sweating
OD on anticholinesterase. Antidote?
Atopine and pralidoxime (regenerates AChE)
Homatropine and tropicamide used for?
Dilate eye
Ipratropium and trotropium used for?
Muscarinic Antag. MoA of drug used to reduce symptoms of COPD and asthma
Reduces urgency in cystitis and reduces bladder spasms?
oxybutynin
TX for ulcers and to reduce airway secretions?
Glycopyrrolate
Methcopolamine
Antimuscarinic for ulcers
Order of first 3 atropine OD effects?
Dry
Blind
Hot
Atropine effects on heart?
Low dose - bradycardia
High dose - tachycardia
Use of Isoproerenol?
Tosade de pointes
Used for renal shock and heart failure?
DA
Used for priapism and as a decongestant?
Phenylephine
