cardio 2 Flashcards

1
Q

describe the order from impulse at SA to ventricular contracttion

A

SA -> ATRIA -> AV NODE -> boh -> purkinje -> ventricles

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2
Q

what is desirable for the treatment of supraventricular arrhythmias

A

AV block

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3
Q

where are the fast cardiac APs

A

purkinje, atria, ventricles

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4
Q

describe the phases of a fast AP

A

0 = Na goes in
I = Na goes in to a lesser extent
II = Na and Ca through channels, Na/Ca exchange
III = K goes out (final repolarization(
IV = pacemaker depolarization, Na/K dependent, HCN channels, ionic gradients

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5
Q

desrcibe the phases of a slow AP

A

0 = Na and Ca in
III = K out
IV = Ca dependent pacemaker

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6
Q

What is described by
P
QRS
T
P-R
Q-T

A

atrial depol
ventricular depol
ventricular repol
av conduction time
duration of ventricular AP

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7
Q

what is chronotropy

A

frequency of impulse formation

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8
Q

what is inotropy

A

strength of contraction

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9
Q

how do sympathetic affects change the slope of Phase IV in SA

A

positive chronotropic

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10
Q

what phase does a inotropic effect affect

A

Phase II

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11
Q

how does a positive inotropic effect affect the APs`

A

increase Ca through L-type

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12
Q

how do sympathetics affect AV conduction, how does this affect the P-R

A

increase AV conduction
decrease P-R

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13
Q

how do sympathetics affect ventricular AP duration

A

shortens, higher heart rate

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14
Q

how does sympathetic affect Purkinje fibres?

A

increase rhythmicitty, increasing slope, quicker threshold

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15
Q

what is the consequence of calcium overload

A

EADs DADs

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16
Q

what nerve is most significant in parasympathetic signalling to the heart

A

vagus

17
Q

what receptors are responsible for parasympathetic activity on the heart

A

M2

18
Q

what is the mechanism behind M2

A

Gi

19
Q

do parasympathetic signaling have an inotropic effect `

A

nah

20
Q

what affect does parasympathetic signaling have on the heart

A

negative chronotropic
atria
AV node

21
Q

which node is responsible for the chronotopics effect of parasympathetic signaling

A

SA node