Cardiac Infections Flashcards
1
Q
Infective endocarditis
A
Infection of endothelium of heart valves
2
Q
Infective endocarditis predisposing factors
A
Heart valve abnormality
Prosthetic heart valve
IV drug user
IV lines
3
Q
Pathogenesis of endocarditis
A
Heart valve damaged Turbulent blood flow over roughened endothelium Platelets deposited Bacteraemia (eg. from dental treatment) Organisms settle in platelet thrombi Vegetations break off
4
Q
Infective endocarditis organisms
A
Staph aeurus (38%) Strep Viridans (31%)
5
Q
Unusual organisms causing infective endocarditis
A
Coxiella burnetti
HACEK
Fungi
6
Q
Coagulase test
A
distinguishes between staphylococcus aureus
7
Q
Staph auerus
A
common in prosthetic material (valves)
IV lines
8
Q
Symptoms of infective endocarditis
A
Overwhelming sepsis Cardiac failure Fever Malaise Weight loss SOB Tiredness
9
Q
Treatment of Infective Endocarditis
A
Viridans strep = amoxicillin
Prosthetic Valve = vancomycin + gentamicin
IV user = flucloxacillin
