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Heme-Onc > Carcinogens > Flashcards

Carcinogens Flashcards

1
Q

cancer associated with aflotoxins

A

hepatocellular carcinoma

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2
Q

carcinogen derived from aspergillus, which can contaminate stored grain

A

aflotoxins

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3
Q

cancer associated with alkylating agents

A

leukemia/lymphoma

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4
Q

carcinogen that causes the increased incidence of leukemia/lymphoma secondary to chemotherapy

A

alkylating agents

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5
Q

cancer associated with alcohol

A

squamous cell carcinoma of oropharynx and upper esophagus
pancreatic carcinoma
hepatocellular carcinoma

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6
Q

2 main carcinogens associated with carcinoma of oropharynx

A

alcohol

tobacco

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7
Q

cancer associated with arsenic

A 
squamous cell carcinoma of skin
lung cancer (present in cigarette smoke)
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8
Q

cancer associated with asbestos

A

lung carcinoma

mesothelioma

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9
Q

carcinogen in cigarette smoke that is particularly carcinogenic

A

polycyclic hydrocarbons

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10
Q

cancer associated with cigarette smoke

A

carcinoma of oropharynx, esophagus, lung

carcinoma of kidney, bladder

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11
Q

cancer associated with nitrosamines

A

stomach carcinoma (intestinal type)

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12
Q

carcinogen responsible for high rate of stomach carcinoma in Japan

A

nitrosamines

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13
Q

carcinogen found in smoked foods

A

nitrosamines

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14
Q

cancer associated with naphthylamine

A

urothelial carcinoma of bladder

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15
Q

carcinogen derived from cigarette smoke that is associated with carcinoma of the bladder

A

naphthylamine

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16
Q

cancer associated with vinyl chloride

A

angiosarcoma of liver

17
Q

occupational exposure to this is associated with angiosarcoma of liver

A

PVC (in pipes)

18
Q

cancer associated with nickel, chromium, berrylium, or silica (occupational exposures)

A

lung carcinoma

19
Q

cancer associated with EBV

A

nasopharyngeal carcinoma
Burkitt lymphoma
CNS lymphoma in AIDS

20
Q

2 groups of people prone to EBV-related nasopharyngeal carcinoma

A

chinese males

african individuals

21
Q

cancer associated with HHV-8

A

kaposi sarcoma

22
Q

cancer associated with HBV and HCV

A

hepatocellular carcinoma

23
Q

cancer associated with HTLV-1

A

adult T-cell leukemia/lymphoma

24
Q

High risk HPV

A

squamous cell carcinoma of vulva, vagina, anus, cervix

adenocarcinoma of cervix

25
Q

cancer associated with ionizing radiation (e.g. nuclear reactor accident)

A

papillary carcinoma of thyroid

AML, CML

26
Q

mechanism by which ionizing radiation increases cancer risk

A

generates hyroxyl free radicals

27
Q

cancer associated with nonionizing radiation (e.g. UVB sunlight)

A

basal cell carcinoma of skin
squamous cell carcinoma of skin
melanoma of skin

28
Q

mechanism by which nonionizing radiation increase cancer risk

A

formation of pyrimidine dimers in DNA (normally excised by restriction endonuclease)

Heme-Onc (11 decks)

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