Carcinogens Flashcards

1
Q

cancer associated with aflotoxins

A

hepatocellular carcinoma

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2
Q

carcinogen derived from aspergillus, which can contaminate stored grain

A

aflotoxins

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3
Q

cancer associated with alkylating agents

A

leukemia/lymphoma

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4
Q

carcinogen that causes the increased incidence of leukemia/lymphoma secondary to chemotherapy

A

alkylating agents

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5
Q

cancer associated with alcohol

A

squamous cell carcinoma of oropharynx and upper esophagus
pancreatic carcinoma
hepatocellular carcinoma

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6
Q

2 main carcinogens associated with carcinoma of oropharynx

A

alcohol

tobacco

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7
Q

cancer associated with arsenic

A
squamous cell carcinoma of skin
lung cancer (present in cigarette smoke)
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8
Q

cancer associated with asbestos

A

lung carcinoma

mesothelioma

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9
Q

carcinogen in cigarette smoke that is particularly carcinogenic

A

polycyclic hydrocarbons

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10
Q

cancer associated with cigarette smoke

A

carcinoma of oropharynx, esophagus, lung

carcinoma of kidney, bladder

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11
Q

cancer associated with nitrosamines

A

stomach carcinoma (intestinal type)

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12
Q

carcinogen responsible for high rate of stomach carcinoma in Japan

A

nitrosamines

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13
Q

carcinogen found in smoked foods

A

nitrosamines

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14
Q

cancer associated with naphthylamine

A

urothelial carcinoma of bladder

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15
Q

carcinogen derived from cigarette smoke that is associated with carcinoma of the bladder

A

naphthylamine

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16
Q

cancer associated with vinyl chloride

A

angiosarcoma of liver

17
Q

occupational exposure to this is associated with angiosarcoma of liver

A

PVC (in pipes)

18
Q

cancer associated with nickel, chromium, berrylium, or silica (occupational exposures)

A

lung carcinoma

19
Q

cancer associated with EBV

A

nasopharyngeal carcinoma
Burkitt lymphoma
CNS lymphoma in AIDS

20
Q

2 groups of people prone to EBV-related nasopharyngeal carcinoma

A

chinese males

african individuals

21
Q

cancer associated with HHV-8

A

kaposi sarcoma

22
Q

cancer associated with HBV and HCV

A

hepatocellular carcinoma

23
Q

cancer associated with HTLV-1

A

adult T-cell leukemia/lymphoma

24
Q

High risk HPV

A

squamous cell carcinoma of vulva, vagina, anus, cervix

adenocarcinoma of cervix

25
cancer associated with ionizing radiation (e.g. nuclear reactor accident)
papillary carcinoma of thyroid | AML, CML
26
mechanism by which ionizing radiation increases cancer risk
generates hyroxyl free radicals
27
cancer associated with nonionizing radiation (e.g. UVB sunlight)
basal cell carcinoma of skin squamous cell carcinoma of skin melanoma of skin
28
mechanism by which nonionizing radiation increase cancer risk
formation of pyrimidine dimers in DNA (normally excised by restriction endonuclease)