Carbapenems, Glycoproteins, And Lipoproteins Flashcards

1
Q

MOA and use of Carbopenems (Merrem)

A

MOA: Bactericidal, inhibits cell wall
USE: Anaerobic coverage (Bacteroids species), Gramp pos cocci, Gram negative bacteria, UTI, PNA, Intra abdominal, skin and soft tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Carbopenem (Merrem) avoid use and SE

A

Avoid use is atypicals
SE: Elevated LFTs, leukopenia, and seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Glycopeptide (Vancomycin) MOA and use

A

MOA: Bactericidal, binds to cell wall
USE: Gram pos cocci and bacilli, MRSA, MRSE, and ampicillin resistant enterococci, IV for bacteremia, endocarditis, and osteo
PO for c.diff

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Glycopeptide (Vancomycin) avoid use and SE

A

Avoid use in MSSA and gram negatives
SE: Ototoxicity, nephrotoxicity, red mans syndrome, thrombocytopenia, and neutropenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Lipoglycopeptide (Daptomycin) MOA and use

A

MOA: Bactericidal inhibits cell wall
USE: Gram positive, Vanco resistant strains, bacteremia, endocarditis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Lipoglycopeptide (Daptomycin) avoid use and SE

A

Avoid use in pneumonia
SE: C diff., superinfection, thrombocytopenia, and rhabdomyolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly