Capitol 18 Osteonecroza

Question 1

Efect agenti fizici Rterapue asupra celulelor Rssb

Answer 1

Osteocite - afectare turnover, scade vindecarea
Celulele endoteliului vascular - tulburari circulatorii, tromboze

Question 2

Aspecte os expus in ORN

Answer 2

Culoare bruna cenusie
Rugos la palpare

Question 3

Indicatii medicamente antiangiogenice, antiresorbtive

Answer 3

1. Mielom multiplu
2. Metastaze osoase
3. Osteoporoza

Question 4

Indicatii rezectie osoasa in osteomielita

Answer 4

1. Fracturi in os patologic
2. Forme clinice rebele la tratamentul conservator

Question 5

Medicatie asociata cu risc de ORN

Answer 5

antiresorbtive osoase tip inhibitori osteoclaste - BISFOSFONATI
1. ac alendronic
2. clodronat Na
3. risedronat Na
4. ac ibandronic
5. pamidronat diNa
6. ac zoleronic

antiresorbtive osoase tip Ac monoclonali anti-RANKL - DENOSUMAB

antiangiogenice - BEVACIZUMAN + SINITINIB

Question 6

Factori favorizanti ORN

Answer 6

1. stari imunosupresie
2. DZ
3. afectiuni care compromit capacitatea de vindecare

Question 7

Semne specifice Rx stadiu III ORN

Answer 7

1. fracturi mandibula
2. sinuzita maxilara odontogena

Question 8

ORN trece dincolo de PA la nivelul

Answer 8

1. ram mandibular
2. margine bazilara
3. sinus maxilar