Canmeds, Stats & Other (2008-2019) Flashcards
- 4 components of WOMAC (2013)
- Pain (5 items)
- Stiffness (2 items)
- Physical Function (17 items)
- Index/Global Score (summary of 3 subscales)
2.Give 8 steps in the WHO preop checklist to enhance the safety of surgery. (2011, 2012, 2013, 2014)
- confirm identity, consent, and procedure
- Side/site marked
- Anesthesia equipment check completed
- Pulse ox check
- Check allergies
- Assess airway risk
- Confirm expected blood loss and availability of blood products
- Confirm antibiotic prophylaxis administered
- 4 principles for establishing causality (2012)
- Consistency
- Strength of relationship
- Excluding alternative (no plausible alternatives)
- Dose Response
DESC
Bradford Hill’s Criteria for Causality
- Strength of association: a strong association supports causality
- Consistency: causality is more likely if multiple studies show a consistent relationship
- Temporal Relationship: there must be a temporal relationship between exposure and outcome in order for there to be causality
- Dose Response Relationship (aka biological gradient): If there is a relationship between the degree of exposure and the magnitude of effect then there is more likely to be causality
- Specificity: if there is a specific outcome related to a specific exposure, causality is more likely
- Plausibility: whether or not the association is plausible
- Coherence: the cause and effect relationship should not contradict current substantive knowledge
- Analogy: existing similar associations would support causality
- Experiment: causation is more likely if evidence is based on randomized experiments
- Surgeon is conducting an RCT on olecranon fractures. Patient comes into emergency with a fracture that could likely be included. The surgeon is scrubbed in but the OR says they could call for that patient next. Surgeon sends med student to discuss the study and obtain consent. Give 3 problems with this scenario. (2014)
- Med student is not a “qualified representative” who is trained in proper procedures to obtain informed consent
- Medical student is not familiar with the details of the study protocol including required follow up, nor is he/she likely aware of treatment alternatives, risks and benefits to participating, etc
- This is a rushed consent if they are going to be called for next case. “For consent to be informed, prospective participants shall be given adequate time and opportunity to assimilate the information provided, pose any questions they might have, and discuss and consider whether they will participate.”
5.List 5 components of determining capacity to provide consent. (2015, 2016)
CPSO 2007 - Determining capacity to consent
- Does the person understand the conditions for which the specific treatment is being proposed
- Is the person able to explain the nature of treatment and understand relevant information
- Is the person aware of possible outcomes of treatment, alternatives or lack of treatment
- Are the persons’ expectations reasonable
- Is the person able to make a decision and communicate a choice
- Is the person able to manipulate the information rationally
6.List 5 steps in management of a medical error. (2015)
CMPA Website - Disclosing harm from healthcare
- Detect the error and address the error
- Full Disclosure to patients
- Show empathy and apologize
- Full Documentation
- Identify cause and prevent recurrence
7.List 5 methods to help eliminate bias in constructing a randomized control trial.(2015)
JAAOS 2010 Randomized Clinical Trials in Orthopedic Surgery: Strategies to Improve Quantity and Quality
- Centralized random allocation (non tamperable way, aka not envelopes)
- Blinding of assessors at minimum (triple blinding is best)
- Predetermined, objective, valid outcome measures
- Intention to treat analysis
- Appropriate sample size/power
- Adequate follow up period to capture outcome (minimum 80% need to reach for high quality study)
- Name 6 factors for non-therapeutic opioid abuse (2015)
- JAAOS 2015 - The Opioid Epidemic: Impact on Orthopaedic Surgery
- Personal or family history of substance abuse
- Nicotine dependency
- Age < 45 years
- History of depression or psychiatric diagnosis
- Lower level of education
- Pre-injury/Pre-operative opioid use
9.List the 7 CanMeds Components (2010)
- Professional
- Advocate
- Scholar
- Medical Expert
- Communicator
- Leader
- Collaborator
Professional
Communicator/ Collaborator
Leader/ Advocate
Scholar/Medical Expert
10.List 4 Principles of medical ethics (2010)
- Non-maleficence
- Respect for Autonomy
- Beneficence (benefit the patient)
- Justice (fairness)
11.16 y/o F Jehovah witness trauma patient who has lost enough blood to require a blood transfusion. You explain her that she needs blood. She gets agitated when you say this and refuses. Although she is in shock, she seems competent. What ethical principles are in conflict with each other when dealing with this situation? (2011)
- respect for autonomy (pt’s desire as a competent minor to make her own decisions about her body)
- Beneficence (desire to save her life with blood products)
- Non-maleficence (concern about ostracizing her from her family/religious community, and potentially affecting her eternal soul, according to her beliefs, if you provide blood products against her will.)
- (answer from Jess’ head)
12.Which of the following are not important when evaluating an outcome instrument?
- Content
- Cost effectiveness
- Methodology
- Clinical utility
ANSWER: B
- 2013
- Outcome Instruments: Rationale for Their Use (JBJS 2009) Schemitsh is a co-author
- “Terwee et al. proposed a checklist of quality criteria to evaluate the methodological soundness of patient reported outcome instruments. These criteria include: content validity, internal consistency, criterion validity, construct validity, reproducibility (agreement and reliability), responsiveness, floor and ceiling effects, and interpretability.”
- “The most important feature of outcome instruments is their ability to test whether treatment is effective in improving symptoms or function from a patient’s point of view”
- What is ethical principle of “do no harm”
- nonmalefecince
- beneficence
- autonomy
- justice
ANSWER: A
2008
- Non-maleficence –> first, do not harm
- Beneficence - actions that promote wellbeing of others, serves best interest of patient
- Autonomy - right of individuals to self-determine, make informed choices about personal matters
- Justice - moral obligation to act on basis of fair adjudication
- A patient’s right to know his diagnosis is grounded in the principle of:
- Beneficence
- Justice
- Truthfulness
- Autonomy
ANSWER: D
2008
As above
- Someone needs a life-saving amputation, and are already under an anesthetic for another reason. You get a 2nd physician for 2-doc consent and amputate without waking the patient up. You have followed the principle of:
- Autonomy
- Beneficence
- Non-maleficence
- Justice
ANSWER: B
2008
Practitioner should act in the best interest of the patient
- SF-36, some convoluted question
2010
SF-36:
Generalized health measure
- 8 domains:
- Physical function
- Role - physical
- Role - emotional
- Bodily pain
- General health
- Vitality
- Social functioning
- Mental Health
- Summary of physical and mental health
- Does not target a specific age, disease, treatment
- Useful for comparing burden of disease
- Johal and his uncle Bhandari are doing some Indian dance and decide to study volumetric wear rates of THA of different head sizes (22, 26, 30, 32). What would be best method
- T test
- Chi square
- ANOVA
- Linear regression
ANSWER: C
2013
- This is asking about continuous and categorical variables
- ANOVA (Analysis of variance) looks at the differences of means among groups. It is useful for looking at more three or more groups. (Wikipedia)
- Regression analysis estimates the relationships between variables, focusing on relationship between a dependent variable (head size) and an independent variable (volumetric wear).
- T-test looks at only 2 groups of data to see if they are statistically different from each other.
- Chi square is for categorical variables only (Wikipedia)
- I googled actual primary literature on volumetric wear with head sizes and found both ANOVA and linear regression used to analyze the findings… Some used both!
- When plotting a survivorship curve using the Kaplan Meier survivorship analysis, the number of failed is divided by:
- Initial number of procedures
- Total number still being followed
- Number that have already failed
- Number that were lost of follow
ANSWER: B
2013, 2016
Goel MK (Int J Ayuveda Res 2010) Understanding survival analysis: Kaplan-Meier estimate
Kocher (JBJS 2004) Clinical epidemiology and biostatistics a primer for orthopedic surgeons
- Very serious question. Patient has been “Malingering” and “making unreasonable requests”. In regard to ending this relationship the physician should do all the following except:
- Talk with the patient and explain the situation
- Provide written notice to the patient
- Stop seeing the patient once they receive written notice
- Make alternative recommendations for another physician to treat the patient.
ANSWER: C
2013
CMPA “Ending the doctor-patient relationship” article, July 2015 https://www.cmpa-acpm.ca/-/ending-the-doctor-patient-relationship
- You are designing an RCT. You want to analyze patients based on allocation and not the treatment they received. What is the name of this principle?
- block randomization
- intention-to-treat analysis
- some other shit
- as-treated analysis
ANSWER: B
2012
- Intention-to-treat analysis and accounting for missing data in orthopaedic randomized clinical trials JBJS Am 2009
- “The intention-to-treat principle implies that all patients who are randomized in a clinical trial should be analyzed according to their original allocation. This means that patients crossing over to another treatment group and patients lost to follow-up should be included in the analysis as a part of their original group.”
- What is the best study design to capture prevalence
- RCT
- Cohort
- Retrospective
- Cross sectional
ANSWER: D
2012
Cross-sectional studies, otherwise known as cross-sectional analyses, transversal studies, prevalence study
- All are true regarding observational studies EXCEPT?
- May involve observing patients over time
- May involve observing patients at a certain point in time
- Can allow researchers to identify association but not causation
- Interventions are under control of the researchers
ANSWER: D
2014
- Clinical Trial Design. Orthobullets
- Observational:
- Researchers observe patient groups without allocation of intervention
- May be either prospective or retrospective
- May be descriptive or analytic
- Descriptive - useful for obtaining background information for more advance studies
- Examples: case reports, case series, cross-sectional studies
- Analytic - explores the association between a given outcome and a potentially related variable
- Examples: case-control, cohort, meta-analysis