Candida Flashcards
1
Q
5 Most common Candida Spp (Yeast, filamentous)
A
- C. Albicans (50-60% of infections)
- C. Glabrata
- C. Tropicalis
- C. Parapsilosis
- C. Krusei
2
Q
Identify Risk Factors for development of Candidal Infections
A
HIS Past SCANDAL
- Hematologic malignancy (prolonged neutropenia)
- Immundeficiency
- Stem cell treatment
- Prematurity
- Steroids
- Chemotherapy
- Antibiotics
- Neutrophil deficit
- Diabetes
- Abdominal surgery
- Lines
- Also HIV
3
Q
Describe the general clinical manifestations of Candida infections (invasive vs mucosal disease)
A
- Normal Host: Thrush, Vaginitis, Diaper Rash
- Immunocompromised: Oral thrush, esophageal cadidiasis, endophthalmitis, endocarditis, UTI, hepatosplenic abscess, meningitis
- Fever
4
Q
How to Diagnose Candida
A
- From blood… ALWAYS TREAT IF IN BLOOD
- Tissue
5
Q
Recall three antifungals that can be used for the treatment of Candida spp.
A
- Fluconazole
- Amphotericin B
- Caspofungin
6
Q
What is Dermatophytosis?
A
- Superifcial fungal infections (skin)
- Ex. Ringworm, Tinea corporis
- Feet, groin, scalp, and nails are most commonly affected
- Names are Tinea, followed by where it is found!
7
Q
Clinical Presentation of Dermatophytosis?
A
- Annular (circular, ring-shaped) scaling patch with a raised edge (margin) that is inflamed
- typically center is less inflamed than the edge
8
Q
Diagnosis of Dermatophytosis
A
- Direct Microscopy (stains of skin)
- Culture of skin scrapings
9
Q
Treatment of Dermatophytosis
A
- Oral: Fluconazole, Itraconazole, Terbinafine
- Topical: Azole Antifungals, Terbinafine
