Pharm. Adverse Drugs Flashcards
1
Q
Number Needed to Treat (NNT)
A
of patients that need to be treated to prevent one additional bad outcome. Inverse of Absolute Risk Reduction
2
Q
Adverse Drug Reactions
A
Unintended response to a medicine, occurs at normal therapeutic doses! Major cause of morbidity!
3
Q
Major Classes of Drug-Drug Interactions
A
Pharmacodynamic Interaction: One drug changes response to another drug
Pharmaceutical Interactions: Interactions occur prior to drug administration. Two drug solutions mixed prior to infusion.
Pharmacokinetic Interactions: Interaction due to change in blood concentration, change in absorption!
4
Q
Management of Adverse Drug Reactions
A
If dose related… stop or switch drug!
If allergic… discontinue and do not use again! Switch to diff. drug class!
