cancer vejiga Flashcards
clasificioens de grados de ca vesical
1973
-G1
-G2-G3
2004/2022(OMS)
-urothelial neoplasm of low malignant potential (PUNLMP
-low grade
-High grade
en cuanto tiempo se hace la RE-RTUTV
2-6 semanas
factores de riesgo clinicos
edad mayor a 70 años
>3 cm
tumores multiples
definicion BCG refractario
-T1 HG/G3 tumour is present at 3 months
-Ta HG/G3 tumour is present after 3 months and/or at
6 months, after either re-induction or first course of
maintenance
-If CIS (without concomitant papillary tumour) is present at
3 months and persists at 6 months after either re-induction
or first course of maintenance. If patients with CIS present
at 3 months, an additional BCG course can achieve a
complete response in > 50% of cases .
-If HG tumour appears during BCG maintenance therapy*.
BGC recurrente
-Recurrence of HG/G3 tumour after completion of BCG
maintenance, despite an initial response (LE: 3).
tratamiento para los bajo riesgo
una dosis de quimioterapia intravesical
tratamiento adyuvante en riesgo intermedio
dosis completa de BCG
-induccion (semana 6 semanas)
-mantenimiento( semanal x3)
a los 3,6 y 12 meses.
tratamiento adyuvante en riesgo alto
BCG
-Induccion
-mantenimiento 1-3 años
Tratamiento muy alto riesgo
cistectomia radical
BCG unresponsive tumour
BCG unresponsive tumours include all BCG refractory
tumours and those who develop T1/Ta HG recurrence within
6 months of completion of adequate BCG exposure** or
develop CIS within 12 months of completion of adequate
BCG exposure (LE: 4).
Absolute contraindications of BCG
during the first two weeks after TURB;
* in patients with visible haematuria;
* after traumatic catheterisation;
* in patients with symptomatic urinary
tract infection.
disminucion de progression de Ta y T1 tratados con BCG
disminuye 25% riesgo de progresion.
45% para CIS.
numero de ganglios necesarios para linfa pelvica
igual o mayor a 9
cuanto es lo maximo que se puede esperar para realizar prostatectomia radical sin comprometer el pronostico
3 meses
contraindicaciones para realizar una derivacion neovejiga ortotopica
tumor en el cuello
bordes positivos en turetra
tumor en prostata