CA PENE Flashcards

1
Q

% de Px con ca de pene con VPH

A

80%
serotipos 16 y 18
31,33,35,39,45

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2
Q

facteores de riesgo

A

fimosis OR 11-16
Tabaquismo OR 5
VPH

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3
Q

Ca de pene mas frecuente

A

celulas escamosas (95%)

clasico 65%
basaloide(VPH) 4-10%
verrucoso(no VPH)

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4
Q

lesiones premalignas

A

liquen escleroso(BXO)
Enfermedad de Queyrat
Enfermedad de Bowen
condiloma (VPH 16 y 18)
Buschke Lowestein
Leucolpaquia

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5
Q

Lesion circunscrita rojisa, sobrelevada,aterciopelada y humeda.

A

Eritroplasia de Queyrat (progresa a cancer 10% y 2% metastatasisa)

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6
Q

placa rojisa,INDURADA,a menudo ulcerada.

A

Enferemdeda de BOWEN

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7
Q

factores pronosticos anatomopatologicos mas importantes

A

invesion linfovascular
invasion perineural
grado histologico (alto)

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8
Q

tratamiento ca pene NIpe

A

imiquimod
5FU
Laser

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9
Q

tasa de recurrencia local en penectoma parcial

A

4-50%
mrotalidad 0-27%

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10
Q

borde libre en ca de pene

A

4mm
la europea dice 1 mm

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11
Q

Linfadenectomia superficiales
#

A

25 nodos

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12
Q

Ganglio ams frecuentemente involucrado

A

Ganglio de cloquet ( o de Rosenmuller)

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13
Q

porcentaje de enfermedad metastasica en pacientes N0

A

25%

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14
Q

Tratamiento
cN1/cN2

A

linfadenectomia mas QT adyuvante

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15
Q

Tratamiento N3

A

quimioterapia neoadyuvante.

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16
Q

QT adyuvante

A

Cisplatino 3-4ciclos
5FU
Paclitaxel o docetaxel

17
Q

QT Neoadyuvante

A

Cisplatino 4 ciclos y taxano.

18
Q

indicacion para linfa en pacientes N0

A

T1b o alto grado

19
Q

indicacion para penectomia total

A

T2 alta grado o T3>

20
Q

timing de la linfa desde el diagnostico

A

La linfadenectomia inguinal se teiene que hacer maximo en 3 meses

21
Q

hallazgos histologico del VPH

A

koilocitos

22
Q

sindrome paraneoplasico mas comun del sqCC

A

hipercalcemia

23
Q

localizacion del cancer de pene

A

glande (50%)
cuerpo 30%)
prepicio (20%)

24
Q

lingitud minima de cuerpo del pene para poder orina

A

2 cm
de lo contrario es necesario meato perineal

25
Q

cuantos ganglios tiene la parte superficial del allinfa inguinal

A

4-25 ganglios

26
Q
A