Cancer Risk Factors Flashcards
1
Q
Top 4 cancers
A
1- Breast
2- Lung
3- Prostate
4- Bowel
2
Q
Top 5 risk factors
A
1- BMI 2- Low fruit and veg intake 3- Low PA 4- Tobacco 5- Alcohol
3
Q
2 main genes with cncer
A
1- Oncogenes
2- Tumour suppressing genes
4
Q
What do proto onco genes do
A
Encode proteins that help to promote cell division
5
Q
What so tumour suppressing genes do
A
Anti-cancer genes that negatively regulate proliferation
- P53
6
Q
9 hallmarks of Cancer
A
1- Self sufficiency in own growth factors 2- Insensitive to anti-growth factors 3- Evade Apoptosis 4- Limitless Replication potential 5- Sustained angiogenesis 6- Tissue invasion and metastsis 7- Genetic instability and cancer related inflammation 8- Deregulated metabolism 9- Evading immune system
7
Q
Top 9 modifiable risk factors
A
1- Smoking 2- BMI 3- Eat fruit and Veg 4- Alcohol intake 5- Sun care 6- Processed/Red Meat 7- Fibre 8- Activity 9- Salt intake
8
Q
Breast cancer risk factors
A
1- Alcohol 2- Obesity 3- Ageing 4- PA 5- Gender 6-HRT 7- Contraceptive pill
9
Q
Prostate Cancer Risks
A
1- Family History 2- Ageing 3- Obesity 4- Poor Nutrition - Lycopenes 5- High Calcium intake
10
Q
Test associated with prostate cancer
A
Prostate Specific Antigen (PSA)
11
Q
Lung Cancer Risks
A
1-Current Smoker
2- Ex-Smoker
3- Work wth asbestos
4- Family History
12
Q
Bowel Cancer Risks
A
1- Ageing 2- Smoking 3- Family History 4- Obesity 5- Nutrition 6- Low PA 7- Crohns Disease
