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Pharm > Calcium Channel Blockers > Flashcards

Calcium Channel Blockers Flashcards

Test 2

1
Q

What do Ca++ channel blockers do?

A

Inhibit Ca++ influx in material smooth muscle by blocking the calcium channel

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2
Q

What do Ca++ channel blockers Tx?

A

HTN

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3
Q

What drugs are Ca++ channel blockers?

A

-pine (dihydropyridine Ca++ channel blockers)
verapamil
diltiazem

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4
Q

What side effect is associated with ACE inhibitors?

A

Dry, non productive cough

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5
Q

What is angiotensinogen activated by?

A

Renin

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6
Q

What inhibits Renin?

A

Aliskiren

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7
Q

How do you identify ACE inhibitors?

A

-pril

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8
Q

What does ACE inhibitors do?

A

inhibit ACE to prevent angiotensin from converting into angiotensin II

Lowers BP

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9
Q

What are ARBs?

A

Angiotension Receptor Blockers

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10
Q

What do ARBs do?

A

Block angiotensin II

preventing vasoconstriction and the secretion of aldosterone from the adernal gland.

Lower BP

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11
Q

How do you identify an ARBs?

A

-sartan

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12
Q

Drugs: Captopril

A

ACE inhibitor

PROTOTYPE
Prodrug

Eliminated in Kidneys - Duh.

Teratogenesis Dont use while pregnant
Dry cough d/t bradykinin

Lowers BP

Tx: HTN

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13
Q

Why does ACE inhibitors cause a dry cough?

A

Increase in bradykinin

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14
Q

T/F: You should take K+ supplements while on ACE inhibitors

A

F

It will lead to hyperkalemia

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15
Q

-sartan =

A

ARBs

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16
Q

Drugs: Losartan/Valsartan

A

Angiotensin Receptor Blockers

Teratogenesis Dont use while pregnant

Lowers BP

No dry cough

Tx: HTN

17
Q

T/F: All ACE inhibitors are prodrugs

A

T

18
Q

How do you Dx Pulmonary HTN?

A

Echo
Cardiac Cath

19
Q

What is pulmonary HTN?

A

Increased pressure in the pulmonary arteries
Poor prognosis

20
Q

What is the Tx for Pulmonary HTN?

A

Bosentan

21
Q

Drugs: Bosentan

A

Endothelin Receptor Antagonist

Teratogenic

Tx: Pulmonary HTN

22
Q

What is your initial intervention in decreasing BP?

A

Decrease Na intake
Exercise
Lose wt

23
Q

What other drugs can raise your BP?

A

Contraceptives, decongestants, NSAIDs, alcohol, herbal meds

24
Q

Mild HTN can be treated with ____ drug, but _____ therapy is best.

A

one

dual/combo

25
Q

What is HTN urgency?

A

BP >180/110 WITHOUT organ failure

26
Q

What is HTN emergency?

A

BP >180 WITH ORGAN FAILURE!!!!!

27
Q

What is the difference between HTN urgency and HTN emergency?

A

HTN emergency has organ failure and needs IMMEDIATE lowering of the BP and ICU monitoring

28
Q

How do you identify a Ca++ channel blocker?

A

-pine

29
Q

Tx: HTN emergency

A

Nitroprusside

Pharm (30 decks)

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