Calcium Channel Blockers Flashcards
Test 2
What do Ca++ channel blockers do?
Inhibit Ca++ influx in material smooth muscle by blocking the calcium channel
What do Ca++ channel blockers Tx?
HTN
What drugs are Ca++ channel blockers?
-pine (dihydropyridine Ca++ channel blockers)
verapamil
diltiazem
What side effect is associated with ACE inhibitors?
Dry, non productive cough
What is angiotensinogen activated by?
Renin
What inhibits Renin?
Aliskiren
How do you identify ACE inhibitors?
-pril
What does ACE inhibitors do?
inhibit ACE to prevent angiotensin from converting into angiotensin II
Lowers BP
What are ARBs?
Angiotension Receptor Blockers
What do ARBs do?
Block angiotensin II
preventing vasoconstriction and the secretion of aldosterone from the adernal gland.
Lower BP
How do you identify an ARBs?
-sartan
Drugs: Captopril
ACE inhibitor
PROTOTYPE
Prodrug
Eliminated in Kidneys - Duh.
Teratogenesis Dont use while pregnant
Dry cough d/t bradykinin
Lowers BP
Tx: HTN
Why does ACE inhibitors cause a dry cough?
Increase in bradykinin
T/F: You should take K+ supplements while on ACE inhibitors
F
It will lead to hyperkalemia
-sartan =
ARBs