calcium Flashcards

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1
Q

how many g of calcium is in the bones, rest of body and in total

A

bones - 1185g
rest- 15g - 7 in teeth, 7 outside, 1 inside cells
total - 1200g

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2
Q

how many g of phosphorus is in bones, rest of body and total in body

A

bones - 600g
rest - 100g
total - 700g

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3
Q

how many g of magnesium is in bones, rest of body and total in body

A

bones - 15g
rest - 12g
total - 27g

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4
Q

what form does calcium occur in, in the environment and body

A

occurs as calcium carbonate in the environment ; occurs as calcium phosphate in the body.

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5
Q

what does regulation mean in terms of calcium

A

that plasma Ca cannot be used as a measure of calcium status.

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6
Q

calcium is required for the homeostatic control of what

A

of the absorption, excretion, secretion, and deposition – parathyroid hormone (PTH); 1,25 (OH)2 D3; calcitonin

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7
Q

To ascertain nutritional status requires what

A

complex measurements of bone mineral content and/or density

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8
Q

explain relationship between calcium intake and absorption

A

The efficiency of absorption of Ca is higher at low intakes

At low intakes, more Ca is lost in the faeces than is taken in the food; calcium is secreted in the intestinal juices.

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9
Q

on a typical diet the net proportion of calcium absorbed is

A

25-30% of the intake.

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10
Q

what are the 2 routes that calcium can be absorbed by in the intestine

A

Transcellular – active, calbindin-dependent, vit D regulated

Paracellular – passive, concentration-dependent.

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11
Q

what can calcium absorption be improved by

A

– lactose
– amino acids
– casein
– low Ca intake
– ingestion with a meal
– pregnancy
– lactation

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12
Q

what can calcium absorption be reduced by

A

– long chain fatty acids but only with fat malabsorption
– phosphate but only in excess
– phytate from bran
– oxalate
– vit D deficiency
– menopause, old age
– intestinal disease

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13
Q

in bones and teeth the calcium and phosphorus form crystals of what with what kind of structure

A

crystals of hydroxyapatite, Ca10(PO4)6(OH)2, form the rigid structure.

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14
Q

from 15mg/kg/d of calcium in food how much is lost as waste

A

11mg/kg/d as feaces
4mg/kg/d as urine

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15
Q

explain the process of calcium secretion

A

15mg/kg/d is in taken of calcium in food, this goes to intestine where 7mg/kg/d is absorbed to a calcium pool. 4mg/kg/d is used in bones which is turnover (so same come out of bones). 3mg/kg/d of the calcium in the calcium pool goes into digestive juices back into the intestine. the calcium pool then moves to the kidney where 4mg/kg/d of calcium is lost in urine
and 11mg/kg/d of calcium is lost from the intestine through faeces

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16
Q

explain the relationship between growth rate and calcium

A

Higher the rate of growth the higher need of calcium
so is why very young children/ babys need lost calcium

17
Q

explain bone mineral content and calcium between men and women

A

Bone mineral density peaks between 25-30years. From this point, it’s a progressive decline from that peak

Males are more muscular and are bigger so bigger bones and so their bone mineral density peaks higher than the peak for females.
Males calc doesn’t decline at same rate as women
Osteoporosis is more common in elderly females than males. Stopping them from possibly being able to walk without bones breaking.

Physical activity and diet prevent this rapid bone mineralisation decline

18
Q

in Britain how much calcium on average is lost from urine and skin

A

daily urinary losses of 150 mg are found
with 10 mg/d lost from the skin.

19
Q

Assuming that 30% of calcium is absorbed from mixed British diets, it is suggested that about how many mg/d is needed on average, with no allowance for difference in sex.

A

525 mg/d

20
Q

what are the RNI in UK for adults, male and females between ages (11-18) and during lactation

A

Adult RNI: 700 mg/d

higher levels are set for 11-18 year olds:
Male RNI: 1000 mg/d
Female RNI: 800 mg/d

(Lactation: +550 mg/d)

21
Q

can we get calcium from sources other than dairy and calcium

A

yes
but where low intake of milk calcium theres also a low intake of total calcium

22
Q

does skimming milk take away calcium content

A

no

23
Q

describe calcium content in soft and hard cheese

A

Softer the cheese the less calcium , so harder cheeses have more calcium. But is variable

24
Q

name some high calcium sources that are dairy products

A

cows milk,
human milk
skimmed milk
cheddar cheese(made with rennet)
yoghurt
butter
cottage cheese

25
Q

name some high calcium sources that are non dairy

A

baking powder
self raising flour
white flour
wholemeal flour
meat, offal
fish
hard water- found more in south england

Hard water can form a scum on the top , due to its high levels of calcium
Amount of calc in water varies massively and depends on its location

26
Q

the USA has tolerable upper intake of calcium why

A

Because of high Ca intakes from supplements can lead to

nephrolithiasis (kidney stones)
hypercalcaemia
renal insufficiency
reduced absorption of Fe, Zn, Mg, & P

27
Q

what is the safe upper intake value for calcium

A

2500 mg/d