calcium Flashcards
how many g of calcium is in the bones, rest of body and in total
bones - 1185g
rest- 15g - 7 in teeth, 7 outside, 1 inside cells
total - 1200g
how many g of phosphorus is in bones, rest of body and total in body
bones - 600g
rest - 100g
total - 700g
how many g of magnesium is in bones, rest of body and total in body
bones - 15g
rest - 12g
total - 27g
what form does calcium occur in, in the environment and body
occurs as calcium carbonate in the environment ; occurs as calcium phosphate in the body.
what does regulation mean in terms of calcium
that plasma Ca cannot be used as a measure of calcium status.
calcium is required for the homeostatic control of what
of the absorption, excretion, secretion, and deposition – parathyroid hormone (PTH); 1,25 (OH)2 D3; calcitonin
To ascertain nutritional status requires what
complex measurements of bone mineral content and/or density
explain relationship between calcium intake and absorption
The efficiency of absorption of Ca is higher at low intakes
At low intakes, more Ca is lost in the faeces than is taken in the food; calcium is secreted in the intestinal juices.
on a typical diet the net proportion of calcium absorbed is
25-30% of the intake.
what are the 2 routes that calcium can be absorbed by in the intestine
Transcellular – active, calbindin-dependent, vit D regulated
Paracellular – passive, concentration-dependent.
what can calcium absorption be improved by
– lactose
– amino acids
– casein
– low Ca intake
– ingestion with a meal
– pregnancy
– lactation
what can calcium absorption be reduced by
– long chain fatty acids but only with fat malabsorption
– phosphate but only in excess
– phytate from bran
– oxalate
– vit D deficiency
– menopause, old age
– intestinal disease
in bones and teeth the calcium and phosphorus form crystals of what with what kind of structure
crystals of hydroxyapatite, Ca10(PO4)6(OH)2, form the rigid structure.
from 15mg/kg/d of calcium in food how much is lost as waste
11mg/kg/d as feaces
4mg/kg/d as urine
explain the process of calcium secretion
15mg/kg/d is in taken of calcium in food, this goes to intestine where 7mg/kg/d is absorbed to a calcium pool. 4mg/kg/d is used in bones which is turnover (so same come out of bones). 3mg/kg/d of the calcium in the calcium pool goes into digestive juices back into the intestine. the calcium pool then moves to the kidney where 4mg/kg/d of calcium is lost in urine
and 11mg/kg/d of calcium is lost from the intestine through faeces